Test Details
Methodology
Latex agglutination (LA)
Result Turnaround Time
1 - 2 days
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
Use
Detect heterophil antibodies related to infectious mononucleosis
Limitations
Rare patients may have positive heterophil agglutinins after a negative initial test. Ten percent of cases of true EBV mononucleosis may have negative heterophil agglutinins. These may be diagnosed with EBV specific tests.
Custom Additional Information
A positive test in the presence of consistent clinical and/or hematologic findings confirms the diagnosis of infectious mononucleosis. Approximately 10% of mononucleosis syndromes are heterophil-negative. In some of these, antibody to specific Epstein-Barr viral antigen can be demonstrated. Others may be due to CMV, HSV, or toxoplasmosis. Although this classic test has excellent specificity, false-positive tests can occur and may lead to diagnostic confusion.
Specimen Requirements
Specimen
Serum
Volume
1 mL
Minimum Volume
0.5 mL
Container
Red-top tube or gel-barrier tube
Stability Requirements
Temperature | Period |
|---|---|
Room temperature | 14 days |
Refrigerated | 14 days |
Frozen | 14 days |
Freeze/thaw cycles | Stable x3 |
Reference Range
Negative
Storage Instructions
Maintain specimen at room temperature.
LOINC® Map
| Order Code | Order Code Name | Order Loinc | Result Code | Result Code Name | UofM | Result LOINC |
|---|---|---|---|---|---|---|
| 006189 | Mononucleosis Test, Qual | 5213-4 | 006189 | Mononucleosis Test, Qual | 5213-4 | |
| Order Code | 006189 | |||||
| Order Code Name | Mononucleosis Test, Qual | |||||
| Order Loinc | 5213-4 | |||||
| Result Code | 006189 | |||||
| Result Code Name | Mononucleosis Test, Qual | |||||
| UofM | ||||||
| Result LOINC | 5213-4 |