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Red Blood Cell (RBC) Antigen Typing: A1

CPT 86905

Test Details

Methodology

Hemagglutination

Result Turnaround Time

2 - 4 days

Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.

Related Documents

Use

Group A subgroup typing of a potential organ donor for A1 may be important, as it may preclude a solid organ transplant to a group O or group B recipient. ABO antigens are expressed on the vascular endothelium of organs. Major incompatibility between donor ABO antigens and recipient plasma can result in acute humoral rejection of the transplanted organ. The occurrence of the A1 antigen is 34% in Caucasians, 19% in Blacks, and 27% in Asians. A1 is present in 80% of group A individuals.

Special Instructions

For ABO Group, refer to test 006056. For ABO Group and Rh Typing, refer to test 006049.

Limitations

Presence of potent cold agglutinins, a positive direct antiglobulin test, and (in some cases) bacteremia may interfere with test interpretation.

Specimen Requirements

Specimen

Whole blood

Volume

1 mL

Minimum Volume

0.5 mL (Note: This volume does not allow for repeat testing.)

Container

Lavender-top (EDTA) tube

Stability Requirements

Temperature

Period

Room temperature

72 hours

Refrigerated

72 hours

Storage Instructions

Specimens should be tested as soon as possible or within 72 hours of collection. Samples that cannot be tested immediately should be stored at 2°C to 8°C. Do not freeze red cells.

Causes for Rejection

Gross hemolysis; bacterial or other contamination

References

Fung MK, Grossman JB, Hillyer CD, Westoff CM, eds. AABB Technical Manual. 18th ed. Bethesda, Md: American Association of Blood Banks;2014.
Reid ME, Lomas-Frances CG, Olsson ML, eds. Blood Group Antigen Facts Book. 3rd ed. London, England: Academic Press; 2012.

LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
006002 A1 RBC Antigen Typing 844-1 006001 A1 RBC Antigen Typing 844-1
Order Code006002
Order Code NameA1 RBC Antigen Typing
Order Loinc844-1
Result Code006001
Result Code NameA1 RBC Antigen Typing
UofM
Result LOINC844-1