Red Blood Cell (RBC) Antigen Typing: A1

CPT: 86905
Print Share

Special Instructions

For ABO Group, refer to test 006056. For ABO Group and Rh Typing, refer to test 006049.


Expected Turnaround Time

2 - 4 days



Related Documents


Specimen Requirements


Specimen

Whole blood


Volume

1 mL


Minimum Volume

0.5 mL (Note: This volume does not allow for repeat testing.)


Container

Lavender-top (EDTA) tube


Storage Instructions

Specimens should be tested as soon as possible or within 72 hours of collection. Samples that cannot be tested immediately should be stored at 2°C to 8°C. Do not freeze red cells.


Stability Requirements

Temperature

Period

Room temperature

72 hours

Refrigerated

72 hours


Causes for Rejection

Gross hemolysis; bacterial or other contamination


Test Details


Use

Group A subgroup typing of a potential organ donor for A1 may be important, as it may preclude a solid organ transplant to a group O or group B recipient. ABO antigens are expressed on the vascular endothelium of organs. Major incompatibility between donor ABO antigens and recipient plasma can result in acute humoral rejection of the transplanted organ. The occurrence of the A1 antigen is 34% in Caucasians, 19% in Blacks, and 27% in Asians. A1 is present in 80% of group A individuals.


Limitations

Presence of potent cold agglutinins, a positive direct antiglobulin test, and (in some cases) bacteremia may interfere with test interpretation.


Methodology

Hemagglutination


References

Fung MK, Grossman JB, Hillyer CD, Westoff CM, eds. AABB Technical Manual. 18th ed. Bethesda, Md: American Association of Blood Banks;2014.
Reid ME, Lomas-Frances CG, Olsson ML, eds. Blood Group Antigen Facts Book. 3rd ed. London, England: Academic Press; 2012.

LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
006002 A1 RBC Antigen Typing 844-1 006001 A1 RBC Antigen Typing 844-1

For Providers

Please login to order a test

Order a Test

© 2021 Laboratory Corporation of America® Holdings and Lexi-Comp Inc. All Rights Reserved.

CPT Statement/Profile Statement

The LOINC® codes are copyright © 1994-2021, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. Permission is granted in perpetuity, without payment of license fees or royalties, to use, copy, or distribute the LOINC® codes for any commercial or non-commercial purpose, subject to the terms under the license agreement found at https://loinc.org/license/. Additional information regarding LOINC® codes can be found at LOINC.org, including the LOINC Manual, which can be downloaded at LOINC.org/downloads/files/LOINCManual.pdf