Skip to main content

Hemoglobin (Hb) Solubility With Reflex to Hemoglobinopathy Fractionation Cascade, Blood

Test Number 005330
Test number copied
CPT 85660. If reflex testing is performed, concomitant CPT codes/charges will apply.
Synonyms
  • Hb Solubility
  • Sickle Cell Preparation
  • Sickle Cell Solubility Test
  • Sickle Cell Test
  • Sickle Prep
  • Sickledex™

Test Details

Methodology

Sodium hydrosulfite reduction

Result Turnaround Time

2 - 3 days

Use

Qualitative determination of presence of hemoglobin S; detect sickling hemoglobins; evaluate hemolytic anemia, undiagnosed hereditary anemia with morphologic (sickle-like) abnormalities on peripheral blood smear

Specimen Requirements

Test Includes

Hemoglobin (Hb) solubility and automatic reflex to hemoglobin (Hb) fractionation blood (at additional charge), if positive.

Limitations

References

Chehab FF, Kan YW. Detection of sickle cell anaemia mutation by colour DNA amplification. Lancet. 1990 Jan 6; 335(8680):15-17. 1967329
Miale JB. Laboratory Medicine: Hematology. 6th ed. St Louis, Mo: Mosby-Year Book Inc;1982:624-625.

Custom Additional Information

Specimen

Whole blood

Volume

1 mL

Minimum Volume

0.6 mL (Note: This volume does not allow for repeat testing.)

Container

Lavender-top (EDTA) tube; capillary puncture: three microhematocrit tubes

Note: Because this profile reflexes to Hemoglobinopathy Fractionation Cascade [121690] when positive, only a Lavender-top (EDTA) tube is allowed.

Storage Instructions

Room temperature

Causes for Rejection

Specimen other than whole blood received; clotted specimen

Collection Instructions

To avoid delays in turnaround time, please submit a separate lavender-top tube for each test requiring a lavender-top.

Stability Requirements

Temperature

Period

Room temperature

14 days

Refrigerated

14 days

Frozen

14 days

Freeze/thaw cycles

Stable x3

Reference Range

Negative

LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
005330 HB Solu + Rflx Frac 6864-3 005224 Hemoglobin (Hgb) Solubility 6864-3
Order Code005330
Order Code NameHB Solu + Rflx Frac
Order Loinc6864-3
Result Code005224
Result Code NameHemoglobin (Hgb) Solubility
UofM
Result LOINC6864-3
Reflex Table for Hemoglobin (Hgb) Solubility
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 121690 Hgb Fractionation Cascade 121692 Hgb F % 32682-7
Reflex 1
Order Code121690
Order NameHgb Fractionation Cascade
Result Code121692
Result NameHgb F
UofM%
Result LOINC32682-7
Reflex Table for Hemoglobin (Hgb) Solubility
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 121690 Hgb Fractionation Cascade 121693 Hgb A % 20572-4
Reflex 1
Order Code121690
Order NameHgb Fractionation Cascade
Result Code121693
Result NameHgb A
UofM%
Result LOINC20572-4
Reflex Table for Hemoglobin (Hgb) Solubility
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 121690 Hgb Fractionation Cascade 121694 Hgb A2 % 4552-6
Reflex 1
Order Code121690
Order NameHgb Fractionation Cascade
Result Code121694
Result NameHgb A2
UofM%
Result LOINC4552-6
Reflex Table for Hemoglobin (Hgb) Solubility
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 121690 Hgb Fractionation Cascade 121695 Hgb S % 32683-5
Reflex 1
Order Code121690
Order NameHgb Fractionation Cascade
Result Code121695
Result NameHgb S
UofM%
Result LOINC32683-5
Reflex Table for Hemoglobin (Hgb) Solubility
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 121690 Hgb Fractionation Cascade 121696 Interpretation: 12710-0
Reflex 1
Order Code121690
Order NameHgb Fractionation Cascade
Result Code121696
Result NameInterpretation:
UofM
Result LOINC12710-0
Reflex Table for Hemoglobin (Hgb) Solubility
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 121690 Hgb Fractionation Cascade 121696 Interpretation: 12710-0
Reflex 1
Order Code121690
Order NameHgb Fractionation Cascade
Result Code121696
Result NameInterpretation:
UofM
Result LOINC12710-0
Reflex Table for Hemoglobin (Hgb) Solubility
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 121690 Hgb Fractionation Cascade 121696 Interpretation: 12710-0
Reflex 1
Order Code121690
Order NameHgb Fractionation Cascade
Result Code121696
Result NameInterpretation:
UofM
Result LOINC12710-0
Reflex Table for Hemoglobin (Hgb) Solubility
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 121690 Hgb Fractionation Cascade 121696 Interpretation: 12710-0
Reflex 1
Order Code121690
Order NameHgb Fractionation Cascade
Result Code121696
Result NameInterpretation:
UofM
Result LOINC12710-0
Reflex Table for Hemoglobin (Hgb) Solubility
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 121690 Hgb Fractionation Cascade 121696 Interpretation: 12710-0
Reflex 1
Order Code121690
Order NameHgb Fractionation Cascade
Result Code121696
Result NameInterpretation:
UofM
Result LOINC12710-0
Reflex Table for Hemoglobin (Hgb) Solubility
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 121690 Hgb Fractionation Cascade 121696 Interpretation: 12710-0
Reflex 1
Order Code121690
Order NameHgb Fractionation Cascade
Result Code121696
Result NameInterpretation:
UofM
Result LOINC12710-0
Reflex Table for Hemoglobin (Hgb) Solubility
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 121690 Hgb Fractionation Cascade 121696 Interpretation: 12710-0
Reflex 1
Order Code121690
Order NameHgb Fractionation Cascade
Result Code121696
Result NameInterpretation:
UofM
Result LOINC12710-0
Reflex Table for Hemoglobin (Hgb) Solubility
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 121690 Hgb Fractionation Cascade 121696 Interpretation: 12710-0
Reflex 1
Order Code121690
Order NameHgb Fractionation Cascade
Result Code121696
Result NameInterpretation:
UofM
Result LOINC12710-0
Reflex Table for Hemoglobin (Hgb) Solubility
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 121690 Hgb Fractionation Cascade 121696 Interpretation: 12710-0
Reflex 1
Order Code121690
Order NameHgb Fractionation Cascade
Result Code121696
Result NameInterpretation:
UofM
Result LOINC12710-0
Reflex Table for Hemoglobin (Hgb) Solubility
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 121690 Hgb Fractionation Cascade 121696 Interpretation: 12710-0
Reflex 1
Order Code121690
Order NameHgb Fractionation Cascade
Result Code121696
Result NameInterpretation:
UofM
Result LOINC12710-0
Reflex Table for Hemoglobin (Hgb) Solubility
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 121690 Hgb Fractionation Cascade 121696 Interpretation: 12710-0
Reflex 1
Order Code121690
Order NameHgb Fractionation Cascade
Result Code121696
Result NameInterpretation:
UofM
Result LOINC12710-0
Reflex Table for Hemoglobin (Hgb) Solubility
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 121690 Hgb Fractionation Cascade 121696 Interpretation: 12710-0
Reflex 1
Order Code121690
Order NameHgb Fractionation Cascade
Result Code121696
Result NameInterpretation:
UofM
Result LOINC12710-0
Reflex Table for Hemoglobin (Hgb) Solubility
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 121690 Hgb Fractionation Cascade 121696 Interpretation: 12710-0
Reflex 1
Order Code121690
Order NameHgb Fractionation Cascade
Result Code121696
Result NameInterpretation:
UofM
Result LOINC12710-0
Reflex Table for Hemoglobin (Hgb) Solubility
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 121690 Hgb Fractionation Cascade 121696 Interpretation: 12710-0
Reflex 1
Order Code121690
Order NameHgb Fractionation Cascade
Result Code121696
Result NameInterpretation:
UofM
Result LOINC12710-0
Reflex Table for Hemoglobin (Hgb) Solubility
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 121690 Hgb Fractionation Cascade 121696 Interpretation: 12710-0
Reflex 1
Order Code121690
Order NameHgb Fractionation Cascade
Result Code121696
Result NameInterpretation:
UofM
Result LOINC12710-0
Reflex Table for Hemoglobin (Hgb) Solubility
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 121690 Hgb Fractionation Cascade 121696 Interpretation: 12710-0
Reflex 1
Order Code121690
Order NameHgb Fractionation Cascade
Result Code121696
Result NameInterpretation:
UofM
Result LOINC12710-0
Reflex Table for Hemoglobin (Hgb) Solubility
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 121690 Hgb Fractionation Cascade 121696 Interpretation: 12710-0
Reflex 1
Order Code121690
Order NameHgb Fractionation Cascade
Result Code121696
Result NameInterpretation:
UofM
Result LOINC12710-0
Reflex Table for Hemoglobin (Hgb) Solubility
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 121690 Hgb Fractionation Cascade 121696 Interpretation: 12710-0
Reflex 1
Order Code121690
Order NameHgb Fractionation Cascade
Result Code121696
Result NameInterpretation:
UofM
Result LOINC12710-0
Reflex Table for Hemoglobin (Hgb) Solubility
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 121690 Hgb Fractionation Cascade 121696 Interpretation: 12710-0
Reflex 1
Order Code121690
Order NameHgb Fractionation Cascade
Result Code121696
Result NameInterpretation:
UofM
Result LOINC12710-0
Reflex Table for Hemoglobin (Hgb) Solubility
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 121690 Hgb Fractionation Cascade 121696 Interpretation: 12710-0
Reflex 1
Order Code121690
Order NameHgb Fractionation Cascade
Result Code121696
Result NameInterpretation:
UofM
Result LOINC12710-0
Reflex Table for Hemoglobin (Hgb) Solubility
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 121690 Hgb Fractionation Cascade 121696 Interpretation: 12710-0
Reflex 1
Order Code121690
Order NameHgb Fractionation Cascade
Result Code121696
Result NameInterpretation:
UofM
Result LOINC12710-0