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Sedimentation Rate, Modified Westergren

CPT 85652
Synonyms
  • Erythrocyte Sedimentation Rate
  • ESR
  • Westergren Sedimentation Rate

Test Details

Methodology

Modified Westergren; automated and manual methods are employed.

Result Turnaround Time

Within 1 day

Use

Evaluate the nonspecific activity of infections, inflammatory states, autoimmune disorders, and plasma cell dyscrasias

Specimen Requirements

Limitations

Optimum results are from blood less than two hours old. The ESR is of limited diagnostic value in severe anemia or in hematologic states that affect increased size and shape variation (poikilocytosis) of the RBC (ie, presence of sickle cells or spherocytes). Extreme plasma viscosity will result in a decreased ESR.

References

Gambino SR, Dire JJ, Monteleone M, et al. The Westergren sedimentation rate using K3 EDTA. Tech Bull Regist Med Technol. 1965; 35:1-8.
Harmening D. Clinical Hematology and Fundamentals of Hemostasis. 2nd ed. Philadelphia, Pa: Lippincott;1992:532-534.

Custom Additional Information

Elevations in fibrinogen, α- and β-globulins (acute phase reactants), and immunoglobulins increase the sedimentation rate of red cells through plasma. The test is important in the diagnosis of temporal arteritis, as well as its management.1

Specimen

Whole blood

Volume

Tube fill capacity

Minimum Volume

2 mL (Note: This volume does not allow for repeat testing.)

Container

Lavender-top (EDTA) tube

Storage Instructions

Refrigerate

Causes for Rejection

Hemolysis; clotted specimen; underfilled tube; specimen older than 24 hours; improper labeling; transfer tubes with whole blood; specimen received in any anticoagulant other than EDTA; specimen diluted or contaminated with IV fluid; patient specimen with presence of cold agglutinins or cryoglobulins; specimen received with plasma removed

Collection Instructions

Invert tube immediately 8 to 10 times once tube is filled at time of collection.

Stability Requirements

Temperature

Period

Refrigerated

24 hours

Reference Range

• Male: 0 to 50 years: 0−15 mm/hour, 50 years and older: 0−30 mm/hour

• Female: 0 to 50 years: 0−32 mm/hour, 50 years and older: 0−40 mm/hour

Footnotes

1. Wong RL, Korn JH. Temporal arteritis without an elevated erythrocyte sedimentation rate. Case report and review of the literature. Am J Med. 1986; 80(5):959-964.3518441

LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
005215 Sedimentation Rate-Westergren 4537-7 005215 Sedimentation Rate-Westergren mm/hr 4537-7
Order Code005215
Order Code NameSedimentation Rate-Westergren
Order Loinc4537-7
Result Code005215
Result Code NameSedimentation Rate-Westergren
UofMmm/hr
Result LOINC4537-7