Immunofixation (IFE) and Protein Electrophoresis, Cerebrospinal Fluid

TEST: 001438
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CPT: 84157; 84166; 86335
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Synonyms

  • CSF IEP
  • CSF IFE
  • CSF Immunoelectrophoresis
  • CSF Immunofixation
  • Globulins, CSF
  • IFE/Protein Electrophoresis, CSF

Test Includes

Immunofixation of CSF; CSF protein electrophoresis

Special Instructions

The request form should include patient's age and clinical diagnosis.

Expected Turnaround Time

4 - 8 days

Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.

Related Documents

For more information, please view the literature below.

Published Plasma Cell Dyscrasias Selection Table

Specimen Requirements

Specimen

Cerebrospinal fluid (CSF)

Volume

5 mL

Minimum Volume

2 mL (Note: This volume does not allow for repeat testing.)

Container

Sterile container

Storage Instructions

Refrigerate

Causes for Rejection

Bloody CSF; less than 2 mL CSF

Test Details

Use

Evaluate possible multiple sclerosis, subacute sclerosing panencephalitis, and other chronic CNS disorders associated with local IgG synthesis

Methodology

Agarose gel immunofixation (IFE); protein electrophoresis on agarose media

Reference Interval

Normal pattern

LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
001438 IFE and PE, CSF 143800 IFE, CSF 13174-8
001438 IFE and PE, CSF 002055 Protein, Total, CSF mg/dL 2880-3
001438 IFE and PE, CSF 143826 Pre-Albumin, CSF % 13973-3
001438 IFE and PE, CSF 143834 Albumin, CSF % 13974-1
001438 IFE and PE, CSF 143842 Alpha-1-Globulin, CSF % 13972-5
001438 IFE and PE, CSF 143859 Alpha-2-Globulin, CSF % 13975-8
001438 IFE and PE, CSF 143867 Beta Globulin, CSF % 13976-6
001438 IFE and PE, CSF 143876 Gamma Globulin, CSF % 13977-4
001438 IFE and PE, CSF 122370 PDF 11502-2

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