Test Details
Methodology
Agglutination
Result Turnaround Time
1 - 4 days
Use
This syphilis VDRL is a nontreponemal assay used to aid in the diagnosis of neurosyphilis.
Specimen Requirements
Custom Additional Information
A positive VDRL in a spinal fluid uncontaminated by serum is essentially diagnostic of neurosyphilis; however, a negative test may occur in 30% of patients with tabes dorsalis. The CSF VDRL may take years to become nonreactive after adequate therapy. In AIDS patients, serial CSF VDRL determinations may be needed when neurosyphilis is suspected. By requiring either a positive plasma RPR or FTA-ABS, seropositivity of CSF VDRL could increase to 90%.
Specimen
Cerebrospinal fluid (CSF)
Volume
1 mL
Minimum Volume
0.2 mL (Note: This volume does not allow for repeat testing.)
Container
Sterile tube
Storage Instructions
Refrigerate.
Causes for Rejection
Hemolysis; gross bacterial contamination
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 14 days |
| Refrigerate | 14 days |
| Frozen | 14 days |
| Freeze/Thaw Cycle | Stable x3 |
Reference Range
Nonreactive
LOINC® Map
| Order Code | Order Code Name | Order Loinc | Result Code | Result Code Name | UofM | Result LOINC |
|---|---|---|---|---|---|---|
| 006445 | VDRL, CSF | 22459-2 | 006445 | VDRL, CSF | 22459-2 | |
| Order Code | 006445 | |||||
| Order Code Name | VDRL, CSF | |||||
| Order Loinc | 22459-2 | |||||
| Result Code | 006445 | |||||
| Result Code Name | VDRL, CSF | |||||
| UofM | ||||||
| Result LOINC | 22459-2 |