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Urine Cytology

CPT 88112
Synonyms
  • Urine, Bladder Washings/Lavage

Test Details

Methodology

The fluid will be centrifuged, supernatant poured off, and diagnostic cells aspirated from the remaining material. Filters, monolayers, and/or cytospins will be made along with a cell block, if applicable. Microscopic examination is performed.

Result Turnaround Time

2 - 6 days

Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.

Use

Establish the presence of primary or metastatic neoplasms; aid in the diagnosis of infections with herpesvirus, cytomegalovirus, Blastomyces, and Schistosoma; evaluate malacoplakia; establish the presence of cytomegalic inclusion disease

Special Instructions

Include patient's name, date of birth, sex, Social Security number, previous malignancy, drug therapy, radiation therapy, and all other pertinent clinical information, including history of alcohol abuse, on the request form. A first morning voided specimen is not suitable. Collection method must be identified. For CMV Study, indicate chemotherapy or immunosuppression.

Limitations

Low-grade papillary transitional cell or urothelial carcinomas may not be diagnosed by cytologic examination. Calculi or recent instrumentation may produce atypical changes in urothelial cells simulating malignancy. Chemotherapy and radiation may also produce changes stimulating neoplasia. Viral culture is the method of choice for the diagnosis of CMV but cytology can provide faster results.

Specimen Requirements

Specimen

Second morning specimen; voided or catheterized urine; intraoperative washings of urinary bladder, urethra, ureters, or renal pelvis

Volume

Not less than 20 mL

Container

Sterile plastic urine container

Collection Instructions

Have patient drink one glass (6 oz) every 15 minutes for two to three hours. At the end of two hours, have the patient void or catheterize. Discard specimen.

Technique I (routine): One hour after collection of discarded specimen, have patient void and save the specimen. Send labeled specimen to the laboratory immediately.

Technique II (when residual bladder urine is present): Thirty minutes to one hour after collection of discarded specimen, catheterize bladder. Send labeled specimen to the laboratory immediately.

Technique III (for detection of upper urinary tract lesions): Catheterize ureters to pelvis for suspected renal or pelvic lesions. Repeat procedure using either ureter for control. For ureteral lesion, catheterize ureter to a point just below the level of the suspected lesion. Catheterize other ureter for control. Collect urine for 30 minutes. Label appropriately, right and left ureteral or pelvic specimen. Ship specimen immediately to the laboratory.

Storage Instructions

If collected after hours, add equal amount of 50% ethyl alcohol or Saccomanno fixative and place in the laboratory refrigerator. (Note: Specimens prepared with fixatives that contain 50% ethyl alcohol, eg, Saccomanno fixative, are not acceptable for microbiology testing.) Specify source of specimen.

Patient Preparation

Hydrate patient (give several glasses of water 30 minutes to one hour prior to collection).

Causes for Rejection

Improper labeling; improper fixation; 24-hour collection; undue delay in transport; specimen submitted in vial that expired according to manufacturer's label; frozen specimen

LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
009068 Urine Cytology 47525-1 191115 Specimen type: 22633-2
009068 Urine Cytology 47525-1 191152 Source: 22633-2
009068 Urine Cytology 47525-1 191160 Clinician provided ICD9: 52797-8
009068 Urine Cytology 47525-1 191174 Clinician provided ICD10: 52797-8
009068 Urine Cytology 47525-1 191118 DIAGNOSIS: 47526-9
009068 Urine Cytology 47525-1 191165 Recommendation: 22638-1
009068 Urine Cytology 47525-1 191140 Comment: 22638-1
009068 Urine Cytology 47525-1 191157 Pathologist provided ICD9: 52797-8
009068 Urine Cytology 47525-1 191175 Pathologist provided ICD10: 52797-8
009068 Urine Cytology 47525-1 191117 Clinical history: 22636-5
009068 Urine Cytology 47525-1 191126 Amended report: N/A
009068 Urine Cytology 47525-1 191127 Addendum: 22639-9
009068 Urine Cytology 47525-1 191147 Diagnosis provided by: N/A
009068 Urine Cytology 47525-1 191119 Signed out by: 19139-5
009068 Urine Cytology 47525-1 191120 Performed by: N/A
009068 Urine Cytology 47525-1 191116 Gross description: 22634-0
009068 Urine Cytology 47525-1 191156 Microscopic description: 22635-7
009068 Urine Cytology 47525-1 191141 Special procedure: N/A
009068 Urine Cytology 47525-1 191179 Previous history: N/A
009068 Urine Cytology 47525-1 191144 QA comment: N/A
009068 Urine Cytology 47525-1 019018 . 11546-9
009068 Urine Cytology 47525-1 000000 NonGyn CPT Code Automation N/A
009068 Urine Cytology 47525-1 019065 PDF N/A
009068 Urine Cytology 47525-1 191167 Photomicrograph N/A
Order Code009068
Order Code NameUrine Cytology
Order Loinc47525-1
Result Code191115
Result Code NameSpecimen type:
UofM
Result LOINC22633-2
Order Code009068
Order Code NameUrine Cytology
Order Loinc47525-1
Result Code191152
Result Code NameSource:
UofM
Result LOINC22633-2
Order Code009068
Order Code NameUrine Cytology
Order Loinc47525-1
Result Code191160
Result Code NameClinician provided ICD9:
UofM
Result LOINC52797-8
Order Code009068
Order Code NameUrine Cytology
Order Loinc47525-1
Result Code191174
Result Code NameClinician provided ICD10:
UofM
Result LOINC52797-8
Order Code009068
Order Code NameUrine Cytology
Order Loinc47525-1
Result Code191118
Result Code NameDIAGNOSIS:
UofM
Result LOINC47526-9
Order Code009068
Order Code NameUrine Cytology
Order Loinc47525-1
Result Code191165
Result Code NameRecommendation:
UofM
Result LOINC22638-1
Order Code009068
Order Code NameUrine Cytology
Order Loinc47525-1
Result Code191140
Result Code NameComment:
UofM
Result LOINC22638-1
Order Code009068
Order Code NameUrine Cytology
Order Loinc47525-1
Result Code191157
Result Code NamePathologist provided ICD9:
UofM
Result LOINC52797-8
Order Code009068
Order Code NameUrine Cytology
Order Loinc47525-1
Result Code191175
Result Code NamePathologist provided ICD10:
UofM
Result LOINC52797-8
Order Code009068
Order Code NameUrine Cytology
Order Loinc47525-1
Result Code191117
Result Code NameClinical history:
UofM
Result LOINC22636-5
Order Code009068
Order Code NameUrine Cytology
Order Loinc47525-1
Result Code191126
Result Code NameAmended report:
UofM
Result LOINCN/A
Order Code009068
Order Code NameUrine Cytology
Order Loinc47525-1
Result Code191127
Result Code NameAddendum:
UofM
Result LOINC22639-9
Order Code009068
Order Code NameUrine Cytology
Order Loinc47525-1
Result Code191147
Result Code NameDiagnosis provided by:
UofM
Result LOINCN/A
Order Code009068
Order Code NameUrine Cytology
Order Loinc47525-1
Result Code191119
Result Code NameSigned out by:
UofM
Result LOINC19139-5
Order Code009068
Order Code NameUrine Cytology
Order Loinc47525-1
Result Code191120
Result Code NamePerformed by:
UofM
Result LOINCN/A
Order Code009068
Order Code NameUrine Cytology
Order Loinc47525-1
Result Code191116
Result Code NameGross description:
UofM
Result LOINC22634-0
Order Code009068
Order Code NameUrine Cytology
Order Loinc47525-1
Result Code191156
Result Code NameMicroscopic description:
UofM
Result LOINC22635-7
Order Code009068
Order Code NameUrine Cytology
Order Loinc47525-1
Result Code191141
Result Code NameSpecial procedure:
UofM
Result LOINCN/A
Order Code009068
Order Code NameUrine Cytology
Order Loinc47525-1
Result Code191179
Result Code NamePrevious history:
UofM
Result LOINCN/A
Order Code009068
Order Code NameUrine Cytology
Order Loinc47525-1
Result Code191144
Result Code NameQA comment:
UofM
Result LOINCN/A
Order Code009068
Order Code NameUrine Cytology
Order Loinc47525-1
Result Code019018
Result Code Name.
UofM
Result LOINC11546-9
Order Code009068
Order Code NameUrine Cytology
Order Loinc47525-1
Result Code000000
Result Code NameNonGyn CPT Code Automation
UofM
Result LOINCN/A
Order Code009068
Order Code NameUrine Cytology
Order Loinc47525-1
Result Code019065
Result Code NamePDF
UofM
Result LOINCN/A
Order Code009068
Order Code NameUrine Cytology
Order Loinc47525-1
Result Code191167
Result Code NamePhotomicrograph
UofM
Result LOINCN/A