Test Details
Methodology
Inductively-coupled plasma/mass spectrometry (ICP/MS)
Result Turnaround Time
4 - 6 days
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
Test Includes
Creatinine, urine; thallium, urine; thallium:creatinine ratio
Use
Monitor industrial exposure to thallium
Special Instructions
Do not use preservative. Preservatives used for routine analysis may contain mercuric oxide (ie, Stabilur), which interferes with all metal testing. If both a routine urinalysis and metal testing are ordered, please submit a separate urine specimen (containing no additive) for the metal testing.
Limitations
This test was developed and its performance characteristics determined by LabCorp. It has not been cleared or approved by the Food and Drug Administration.
Custom Additional Information
Thallium exposure, associated with industrial inhalation and/or dermal absorption of metallic thallium or thallium salts, may cause albuminuria, sensory changes, polyneuritis, speech disturbances, weakness, and visual impairment. Ingestion of soluble thallium salts is characterized by colic, nausea, vomiting, tremors, and paralysis.2 Thallium compounds are employed in semiconductor research, optical systems, and photoelectric cells. Thallium salts are also used as insecticides and rodenticides. Poisoning from occupational exposure to thallium can occur in the manufacture of optical instruments, rodenticides, dyes, and certain alloys. Environmental exposure may follow emissions from smelters, cement plants, and coal-fired plants.
Specimen Requirements
Specimen
Urine (random or 24-hour)
Volume
5 mL
Minimum Volume
1.5 mL
Container
Plastic urine container, no preservative
Collection Instructions
Optional protocol: Instruct the patient to void at 8 AM and discard the specimen. Then collect all urine including the final specimen voided at the end of the 24-hour collection period (ie, 8 AM the next morning). Avoid contact with metal during collection. Screw the lid on securely.
Stability Requirements
Temperature | Period |
|---|---|
Room temperature | 14 days |
Refrigerated | 14 days |
Frozen | 14 days |
Freeze/thaw cycles | Stable x3 |
Reference Range
• Environmental exposure: <0.0−1.5 μg/L
• Thallium:creatinine ratio: 0.0−0.9 μg/g creatinine1
Storage Instructions
Maintain specimen at room temperature.
Footnotes
LOINC® Map
| Order Code | Order Code Name | Order Loinc | Result Code | Result Code Name | UofM | Result LOINC |
|---|---|---|---|---|---|---|
| 706580 | Thallium, Urine | 21558-2 | 706581 | Thallium, Urine | ug/L | 21558-2 |
| 706580 | Thallium, Urine | 21558-2 | 723280 | Creatinine(Crt),U | g/L | 2161-8 |
| 706580 | Thallium, Urine | 21558-2 | 706584 | Thallium/Crt Ratio | ug/g crt | 13469-2 |
| Order Code | 706580 | |||||
| Order Code Name | Thallium, Urine | |||||
| Order Loinc | 21558-2 | |||||
| Result Code | 706581 | |||||
| Result Code Name | Thallium, Urine | |||||
| UofM | ug/L | |||||
| Result LOINC | 21558-2 | |||||
| Order Code | 706580 | |||||
| Order Code Name | Thallium, Urine | |||||
| Order Loinc | 21558-2 | |||||
| Result Code | 723280 | |||||
| Result Code Name | Creatinine(Crt),U | |||||
| UofM | g/L | |||||
| Result LOINC | 2161-8 | |||||
| Order Code | 706580 | |||||
| Order Code Name | Thallium, Urine | |||||
| Order Loinc | 21558-2 | |||||
| Result Code | 706584 | |||||
| Result Code Name | Thallium/Crt Ratio | |||||
| UofM | ug/g crt | |||||
| Result LOINC | 13469-2 |