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- Tetanus Toxin Antibodies
Expected Turnaround Time
1 - 5 days
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
Related Documents
Specimen Requirements
Specimen
Serum
Volume
1 mL
Minimum Volume
0.5 mL
Container
Red-top tube or gel-barrier tube
Storage Instructions
Room temperature; do not freeze.
Stability Requirements
Temperature | Period |
|---|---|
Room temperature | 14 days |
Refrigerated | 14 days |
Frozen | Unstable |
Freeze/thaw cycles | Unstable |
Causes for Rejection
Gross hemolysis; lipemia; bacterial contamination
Test Details
Use
Assess immunity against tetanus by determining levels of circulating antibodies to tetanus toxin or to measure the immune response, postvaccination, in individuals suspected of immunodeficiency disorders
Limitations
Determination of tetanus toxoid antibodies is of no value in assessing the need for prophylactic or therapeutic management. Immunity declines with age, and boosters are recommended every 10 years.
This procedure may be considered by Medicare and other carriers as investigational and, therefore, may not be payable as a covered benefit for patients.
Methodology
Enzyme immunoassay (EIA)
Reference Interval
Nonprotective: <0.1 IU/mL
References
Gergen PJ, McQuillan GM, Kiely M, et al. A population-based serologic survey of immunity to tetanus in the United States. N Engl J Med. 1995; 332(12):761-766. 7862178
Rose NR. Manual of Clinical Immunology. 5th ed. Washington, DC: ASM Press;1997: 470-472.
LOINC® Map
| Order Code | Order Code Name | Order Loinc | Result Code | Result Code Name | UofM | Result LOINC |
|---|---|---|---|---|---|---|
| 163691 | Tetanus Antitoxoid IgG Ab | 53935-3 | 163694 | Tetanus Antitoxoid IgG Ab | IU/mL | 53935-3 |
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