Protein Electrophoresis With Interpretation, 24-Hour Urine With Reflex to IFE, 24-Hour Urine

TEST: 123018
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CPT: 84156; 84166
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Synonyms

  • Urine (24-Hour) Interpretation, Protein Electrophoresis and Reflex to IFE, 24-Hour

Test Includes

24-Hour urine protein electrophoresis with interpretation and automatic reflex to urine immunofixation (at an additional charge) if M-spike is present.

Special Instructions

For random specimens, order test 003715.

Expected Turnaround Time

3 - 5 days

Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.

Related Documents

Specimen Requirements

Specimen

Urine (24-hour)

Volume

20-mL aliquot

Minimum Volume

11-mL aliquot

Container

12-mL plastic transport tube (Labcorp No. 23597) without preservative

Collection

Mix well.

Storage Instructions

Refrigerated (preferred) or room temperature

Stability Requirements

Temperature

Period

Room temperature

14 days

Refrigerated

14 days

Frozen

14 days

Freeze/thaw cycles

Stable x1

Causes for Rejection

Preservative added

Test Details

Use

Work up myeloma, macroglobulinemia of Waldenström, lymphoma, amyloidosis; differentiate between normal renal function, glomerular proteinuria, and tubular proteinuria. Increased glomerular permeability leads to higher concentrations of large proteins in the glomerular filtrate. Diminished tubular reabsorptive capacity results in a marked increase in urinary excretion of low molecular weight proteins.

Methodology

Protein electrophoresis on agarose media; agarose gel immunofixation (IFE) if reflexed

LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
123018 PE+Interp(Rfx IFE), 24-Hr U 013664 Protein,Total,Urine mg/dL 2888-6
123018 PE+Interp(Rfx IFE), 24-Hr U 013219 Prot,24hr calculated mg/24 hr 2889-4
123018 PE+Interp(Rfx IFE), 24-Hr U 133686 Albumin, U % 13986-5
123018 PE+Interp(Rfx IFE), 24-Hr U 133694 Alpha-1-Globulin, U % 13984-0
123018 PE+Interp(Rfx IFE), 24-Hr U 133702 Alpha-2-Globulin, U % 13987-3
123018 PE+Interp(Rfx IFE), 24-Hr U 133710 Beta Globulin, U % 13988-1
123018 PE+Interp(Rfx IFE), 24-Hr U 133728 Gamma Globulin, U % 13989-9
123018 PE+Interp(Rfx IFE), 24-Hr U 133729 M-Spike, % % 42484-6
123018 PE+Interp(Rfx IFE), 24-Hr U 133734 M-Spike, mg/24 hr mg/24 hr 42482-0
123018 PE+Interp(Rfx IFE), 24-Hr U 133800 Please note: 77202-0
123018 PE+Interp(Rfx IFE), 24-Hr U 133731 Comment: 77202-0
123018 PE+Interp(Rfx IFE), 24-Hr U 003724 PDF 11502-2
Reflex Table for Comment:
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 120758 IFE Reflex, 24-hr U 013482 Immunofixation Result, Urine 13440-3

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The LOINC® codes are copyright © 1994-2021, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. Permission is granted in perpetuity, without payment of license fees or royalties, to use, copy, or distribute the LOINC® codes for any commercial or non-commercial purpose, subject to the terms under the license agreement found at https://loinc.org/license/. Additional information regarding LOINC® codes can be found at LOINC.org, including the LOINC Manual, which can be downloaded at LOINC.org/downloads/files/LOINCManual.pdf