Pleural Fluid Cytology

CPT: 88112
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Synonyms

  • Pleural Effusions

Special Instructions

Include patient's name, date of birth, sex, Social Security number, previous malignancy, drug therapy, radiation therapy, and all other pertinent clinical information, including history of alcohol abuse, on the request form.


Expected Turnaround Time

2 - 6 days


Specimen Requirements


Specimen

Pleural fluid


Volume

50 mL or more


Minimum Volume

More than 5 mL


Container

1200-cc Cardinal Health Guardian™ disposable hard canister or 120-mL BD Vacutainer® sterile urine collection cup with integrated sampling device available from the courier service


Collection

Label the container with patient's name, hospital number, room number, date, and type of specimen. Deliver immediately to the Cytology Laboratory. If more than a 24-hour delay is anticipated between collection and receipt in the laboratory, please add the following: 1 mL (1000 units) of heparin for each 300 mL of collected fluid. To the entire volume (up to 1 liter) add an equal volume of 50% ethyl alcohol or Saccomanno fixative. (Note: Specimens prepared with fixatives that contain 50% ethyl alcohol, eg, Saccomanno fixative, are not acceptable for microbiology testing.)


Storage Instructions

After hours, place in the laboratory refrigerator.


Patient Preparation

In order to suspend the cells in the fluid, move the patient into several different positions. Perform the paracentesis.


Causes for Rejection

Improper labeling; contamination due to spillage; improper fixation; specimen submitted in vial that expired according to manufacturer's label; frozen specimen


Test Details


Use

Establish the presence of primary or metastatic neoplasms; aid in the diagnosis of rheumatoid pleuritis, fungal and parasitic infestation of serous cavities


Limitations

Allowing fluid to stand for prolonged period before processing may cause deterioration and artifact. First tapping of fluids of long duration may be degenerated and require a second tap after reaccumulation. Clots may contain diagnostic cells which are unavailable for sampling.


Methodology

The fluid will be centrifuged, supernatant poured off, and diagnostic cells aspirated from the remaining material. Filters, monolayers, and/or cytospins will be made along with a cell block, if applicable. Microscopic examination is performed.


LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
009043 Pleural Fluid Cytology 191115 Specimen type: 22633-2
009043 Pleural Fluid Cytology 191152 Source: 22633-2
009043 Pleural Fluid Cytology 191160 Clinician provided ICD9: 52797-8
009043 Pleural Fluid Cytology 191174 Clinician provided ICD10: 52797-8
009043 Pleural Fluid Cytology 191118 DIAGNOSIS: 47526-9
009043 Pleural Fluid Cytology 191165 Recommendation: 22638-1
009043 Pleural Fluid Cytology 191140 Comment: 22638-1
009043 Pleural Fluid Cytology 191157 Pathologist provided ICD9: 52797-8
009043 Pleural Fluid Cytology 191175 Pathologist provided ICD10: 52797-8
009043 Pleural Fluid Cytology 191117 Clinical history: 22636-5
009043 Pleural Fluid Cytology 191126 Amended report: N/A
009043 Pleural Fluid Cytology 191127 Addendum: 22639-9
009043 Pleural Fluid Cytology 191147 Diagnosis provided by: N/A
009043 Pleural Fluid Cytology 191119 Signed out by: 19139-5
009043 Pleural Fluid Cytology 191120 Performed by: N/A
009043 Pleural Fluid Cytology 191116 Gross description: 22634-0
009043 Pleural Fluid Cytology 191156 Microscopic description: 22635-7
009043 Pleural Fluid Cytology 191141 Special procedure: N/A
009043 Pleural Fluid Cytology 191179 Previous history: N/A
009043 Pleural Fluid Cytology 191144 QA comment: N/A
009043 Pleural Fluid Cytology 019018 . 11546-9
009043 Pleural Fluid Cytology 000000 NonGyn CPT Code Automation N/A
009043 Pleural Fluid Cytology 019065 PDF N/A
009043 Pleural Fluid Cytology 191167 Photomicrograph N/A

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