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Pancreatic Elastase, Fecal

CPT 82653
Synonyms
  • Elastase, Pancreatic

Test Details

Methodology

Chemiluminescent immunoassay (CLIA)

Result Turnaround Time

4 - 6 days

Related Documents

Use

This test can be used for the diagnosis or the exclusion of exocrine pancreatic insufficiency, which may be associated with chronic pancreatitis, cystic fibrosis, carcinoma of the pancreas, diabetes mellitus type 1 (insulin-dependent diabetes mellitus), Shwachman-Diamond syndrome and other etiologies of pancreatic insufficiency.

Specimen Requirements

Custom Additional Information

The polyclonal antibodies used in this assay are specifically directed against defined sequences of the human pancreatic elastase molecule. The enzyme stability is remarkably high despite its proteolytic activity, as elastase is found in feces in about a sixfold concentration as in pancreatic fluid. The determination of enzyme concentration in feces reflects the exocrine secretory capacity of the pancreas.

Specimen

Stool (unpreserved, random)

Volume

3 g

Minimum Volume

1 g (Note: This volume does not allow for repeat testing.)

Container

Screw-capped plastic vial

Storage Instructions

Transport specimen frozen.

Causes for Rejection

Serum or plasma received; stool contaminated with urine; preserved stool received

Collection Instructions

Do not contaminate outside of container. Do not overfill container. Do not use a preservative.

Stability Requirements

Temperature

Period

Room temperature

8 hours (stability provided by manufacturer or literature reference)

Refrigerated

7 days (stability provided by manufacturer or literature reference)

Frozen

12 months (stability provided by manufacturer or literature reference)

Freeze/thaw cycles

Stable x2 (stability provided by manufacturer or literature reference)

Reference Range

• Normal: >200 μg elastase/g fecal material

• Moderate pancreatic insufficiency: 100−200 μg elastase/g fecal material

• Severe pancreatic insufficiency: <100 μg elastase/g fecal material

LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
123234 Pancreatic Elastase, Fecal 25907-7 123236 Pancreatic Elastase, Fecal ug Elast./g 25907-7
Order Code123234
Order Code NamePancreatic Elastase, Fecal
Order Loinc25907-7
Result Code123236
Result Code NamePancreatic Elastase, Fecal
UofMug Elast./g
Result LOINC25907-7