Pancreatic Elastase, Fecal

CPT: 82653
Print Share

Synonyms

  • Elastase, Pancreatic

Expected Turnaround Time

4 - 6 days


Related Documents


Specimen Requirements


Specimen

Stool (unpreserved, random)


Volume

3 g


Minimum Volume

1 g (Note: This volume does not allow for repeat testing.)


Container

Screw-capped plastic vial


Collection

Do not contaminate outside of container. Do not overfill container. Do not use a preservative.


Storage Instructions

Transport specimen frozen.


Stability Requirements

Temperature

Period

Room temperature

8 hours (stability provided by manufacturer or literature reference)

Refrigerated

7 days (stability provided by manufacturer or literature reference)

Frozen

12 months (stability provided by manufacturer or literature reference)

Freeze/thaw cycles

Stable x2 (stability provided by manufacturer or literature reference)


Patient Preparation

This assay does not measure the substituted enzyme (Pancreatin) and, therefore, it is not necessary to stop medication before taking a sample.


Causes for Rejection

Serum or plasma received; stool contaminated with urine; preserved stool received


Test Details


Use

This test can be used for the diagnosis or the exclusion of exocrine pancreatic insufficiency, which may be associated with chronic pancreatitis, cystic fibrosis, carcinoma of the pancreas, diabetes mellitus type 1 (insulin-dependent diabetes mellitus), Shwachman-Diamond syndrome and other etiologies of pancreatic insufficiency.


Methodology

Chemiluminescent immunoassay (CLIA)


Reference Interval

• Normal: >200 μg elastase/g fecal material

• Moderate pancreatic insufficiency: 100−200 μg elastase/g fecal material

• Severe pancreatic insufficiency: <100 μg elastase/g fecal material


Additional Information

The polyclonal antibodies used in this assay are specifically directed against defined sequences of the human pancreatic elastase molecule. The enzyme stability is remarkably high despite its proteolytic activity, as elastase is found in feces in about a sixfold concentration as in pancreatic fluid. The determination of enzyme concentration in feces reflects the exocrine secretory capacity of the pancreas.


LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
123234 Pancreatic Elastase, Fecal 25907-7 123236 Pancreatic Elastase, Fecal ug Elast./g 25907-7

For Providers

Please login to order a test

Order a Test

© 2021 Laboratory Corporation of America® Holdings and Lexi-Comp Inc. All Rights Reserved.

CPT Statement/Profile Statement

The LOINC® codes are copyright © 1994-2021, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. Permission is granted in perpetuity, without payment of license fees or royalties, to use, copy, or distribute the LOINC® codes for any commercial or non-commercial purpose, subject to the terms under the license agreement found at https://loinc.org/license/. Additional information regarding LOINC® codes can be found at LOINC.org, including the LOINC Manual, which can be downloaded at LOINC.org/downloads/files/LOINCManual.pdf