p53 Oncology FISH

CPT: Contact CPT coding department at 800-222-7566, ext 6-8400.
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Synonyms

  • FISH
  • Leukemia FISH
  • Lymphoma FISH

Expected Turnaround Time

3 - 5 days



Specimen Requirements


Specimen

Fixed-cell pellet from a cytogenetic analysis, slides with metaphases and/or interphase nuclei, or bone marrow touch prep slides. Blood, bone marrow, cerebrospinal fluid (CSF), FNA are also acceptable.


Volume

Fixed-cell pellet, three slides, 10 mL blood (adult), 5 mL blood (pediatric), or 3 mL bone marrow


Minimum Volume

Fixed-cell pellet from a cytogenetic analysis, two slides, 5 mL blood (adult), 1 mL blood (pediatric), or 1 mL bone marrow


Container

Green-top (sodium heparin) tube; pediatric Vacutainer® is optimal or lavender-top (EDTA) tube


Collection

Transport to the testing lab at room temperature; use a cool pack or LabCorp transport kit. Do not allow sample to freeze.


Storage Instructions

Maintain specimen at room temperature.


Causes for Rejection

Broken or dirty slides; excessive cellular debris or stained slides; decalcified bone cores; frozen specimen


Test Details


Use

Confirmation/identification of leukemia/lymphoma-related alterations; leukemia/lymphoma monitoring of residual disease, transplants, and indolent clones (see list or call lab for probe availability)


Methodology

Fluorescence in situ hybridization (FISH)


LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
510940 P53 Oncology FISH 510250 Specimen Type 31208-2
510940 P53 Oncology FISH 510251 Cells Counted N/A
510940 P53 Oncology FISH 510254 Cells Analyzed N/A
510940 P53 Oncology FISH 510943 FISH Result 48674-6
510940 P53 Oncology FISH 510257 Interpretation 50398-7
510940 P53 Oncology FISH 510944 Director Review: 48672-0

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