1p,19q Oncology FISH

Test Number 510360

CPT

Contact CPT coding department at 800-222-7566, ext 6-8400.

Synonyms

Astrocytoma
Brain Tumor
FISH
Glioblastoma
Oligodendroglioma

Test Details

Methodology

Fluorescence in situ hybridization (FISH) from formalin-fixed paraffin-embedded (FFPE) tissue (4-micron to 5-micron sections); H&E for pathology review

Fluorescence in situ hybridization (FISH) from formalin-fixed paraffin-embedded (FFPE) tissue (4-micron to 5-micron sections); H&E for pathology review.

Fluorescence in situ hybridization (FISH) from formalin-fixed paraffin-embedded (FFPE) tissue (4-micron to 5-micron sections); H&E for pathology review

Result Turnaround Time

3 - 5 days

Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.

Related Information

Fluorescence in situ Hybridization (FISH), Oncology [510669]

>Fluorescence in situ Hybridization (FISH), Oncology
Oncology Fluorescence in situ Hybridization (FISH)

href="https://Fluorescence in situ Hybridization (FISH), Oncology [510669]">Fluorescence in situ Hybridization (FISH), Oncology [510669]

Use

This test is used for confirmation/identification of cancer-related alterations (associated with oligoglioma).

~~Confirmation/identification of cancer-related alterations (associated with oligoglioma)~~

This test is used for confirmation/identification of cancer-related alterations (associated with oligoglioma).

Special Instructions

There will be an additional charge for processing paraffin block samples or for samples that require culture.

Limitations

Molecular mutations or chromosomal alterations not targeted by the probe included in this profile will not be detected.

This test was developed and its performance characteristics determined by Labcorp. It has not been cleared or approved by the Food and Drug Administration.

Molecular mutations or chromosomal alterations not targeted by the probe included in this profile will not be detected.

This test was developed and its performance characteristics determined by Labcorp. It has not been cleared or approved by the Food and Drug Administration.

Specimen Requirements

Specimen

Formalin-fixed paraffin block or fresh tissue (acceptable at additional charge)

Volume

Five slides (4- to 5-micron thick sections)

Minimum Volume

Three slides (4- to 5-micron thick sections) on positively charged slides. (Note: This volume may not allow for repeat testing.)

Three slides (4- to 5-micron thick sections)

Three slides (4- to 5-micron thick sections) on positively charged slides. (Note: This volume may not allow for repeat testing.)

Container

Green-top (sodium heparin) tube; pediatric Vacutainer® is optimal

Collection Instructions

Utilize sterile technique and Labcorp transport kits when possible.

~~Transport to the testing lab at room temperature; if fresh tumor specimen, sample must arrive in the laboratory within 72 hours of collection~~.

Utilize sterile technique and Labcorp transport kits when possible.

Storage Instructions

Maintain specimen at room temperature.

Causes for Rejection

Improper embedded prep; poor fixation <6 hours and >72 hours; decalcified tissue; broken or dirty slides; absence of tumor or quantity not sufficient for analysis

Improper embedded prep; poor fixation <6 hours and >72 hours; decalcified tissue; broken or dirty slides; absence of tumor or quantity not sufficient for analysis.