Test Details
Methodology
Inductively-coupled plasma/mass spectrometry (ICP/MS)
Result Turnaround Time
2 - 4 days
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
Use
Monitor manganese exposure
Limitations
In evaluating toxicity, the serum level may have returned to normal while the neurological damage persists. In evaluating possible deficiency states, the human deficiency syndrome is poorly defined, making interpretation difficult. Levels are reportedly reduced mildly in epilepsy, and raised in hepatitis or jaundice. Manganese levels are 60% lower than normal in hemodialysis patients.
This test was developed and its performance characteristics determined by LabCorp. It has not been cleared or approved by the Food and Drug Administration.
Custom Additional Information
Toxic exposure may occur from dry cells, fungicide (maneb), and in the steel or chemical industries. Manganese is present in the coloring agents for glass and soap, in paints, varnish and enamel, and in linoleum. It is used in the manufacture of chlorine gas and in lead-free gasoline. Industrial manganese poisoning has been recognized since 1837.
Specimen Requirements
Specimen
Whole blood
Volume
2 mL
Minimum Volume
0.6 mL
Container
Royal blue-top (EDTA) tube; submit original tube.
Collection Instructions
Submit original unopened tube.
Stability Requirements
Temperature | Period |
|---|---|
Room temperature | 7 days |
Reference Range
8.0−18.7 μg/L
Storage Instructions
Maintain specimen at room temperature.
Causes for Rejection
Royal blue-top tube not submitted
References
LOINC® Map
| Order Code | Order Code Name | Order Loinc | Result Code | Result Code Name | UofM | Result LOINC |
|---|---|---|---|---|---|---|
| 724195 | Manganese, Blood | 5681-2 | 724196 | Manganese, Blood | ug/L | 5681-2 |
| Order Code | 724195 | |||||
| Order Code Name | Manganese, Blood | |||||
| Order Loinc | 5681-2 | |||||
| Result Code | 724196 | |||||
| Result Code Name | Manganese, Blood | |||||
| UofM | ug/L | |||||
| Result LOINC | 5681-2 |