Iodine, Serum or Plasma

CPT: 83789
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Expected Turnaround Time

2 - 4 days


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Specimen Requirements


Specimen

Serum or plasma


Volume

0.5 mL


Minimum Volume

0.4 mL


Container

Royal blue-top (EDTA) tube or royal blue-top tube without EDTA


Collection

Separate serum or plasma immediately after the collection, and transfer to a certified metal-free transport tube (PeopleSoft No. 111166) for shipment to the laboratory.


Storage Instructions

Maintain specimen at room temperature.


Stability Requirements

Temperature

Period

Room temperature

14 days

Refrigerated

14 days

Frozen

14 days

Freeze/thaw cycles

Stable x3


Causes for Rejection

Certified metal-free plastic transport tube not submitted


Test Details


Use

Monitor exposure to iodine; evaluate for iodine deficiency disorders (IDDs), excessive iodine intake, or iodine in the workplace

IDDS by Age Group

Age Groups

Health Consequences of Iodine Deficiency

Zimmerman MB. Iodine deficiency. Endocrine Reviews. The Endocrine Society. 2009; 30:376-408.

All ages

Goiter

Increased susceptibility of thyroid gland to nuclear radiation

Fetus

Abortion

Stillbirth

Congenital anomalies

Perinatal mortality

Neonates

Infant mortality

Endemic cretinism

Children and adolescents

Impaired mental function

Delayed physical development

Adults

Impaired mental function

Reduced work productivity

Toxic nodular goiter; iodine-induced hyperthyroidism

Increased occurrence of hypothyroidism in moderate-to-severe iodine deficiency; decreased occurrence of hypothyroidism in mild-to-moderate iodine deficiency

Other forms of thyroid problems, namely iodine-induced hypothyroidism, autoimmune thyroiditis, and hyperthyroidism associated with excessive iodine intake have become a greater concern than deficiency disorders.1


Limitations

This test was developed and its performance characteristics determined by LabCorp. It has not been cleared or approved by the Food and Drug Administration.


Methodology

Inductively coupled plasma/mass spectrometry (ICP/MS)


Reference Interval

40.0−92.0 μg/L


Footnotes

1. Hollowell JG, Staehling NW, Hannon WH, et al. Iodine nutrition in the United States, trends and public health implications: Iodine excretion data from National Health and Nutrition Examination Surveys I and III (1971-1974 and 1988-1994). J Clin Endocrinol Metab. 1998; 83(10):3401-3408.9768638

LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
070034 Iodine, Serum or Plasma 2494-3 070035 Iodine, Serum or Plasma ug/L 2494-3

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