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Fluorescence in situ Hybridization (FISH), Paraffin Block

CPT Contact CPT coding department at 800-222-7566, ext 6-8400.
Synonyms
  • Cytogenetics Fluorescence in situ Hybridization on Paraffin-embedded Tissue

Test Details

Methodology

Fluorescence in situ hybridization (FISH) from formalin-fixed tissue-embedded paraffin (4-micron to 5-micron sections); H&E for pathology review.

Result Turnaround Time

5 - 7 days

Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.

Related Documents

Use

For specific FISH probe analysis of tissue specimens

Special Instructions

This test number is used for tracking FISH paraffin samples to the testing facility. Billing will occur after testing is completed.

Pertinent medical findings and probe desired must accompany request for FISH. If prior chromosome analysis has been performed, include a copy of the report. Please direct questions to genetics customer service at 800-345-4363.

Limitations

Samples in formaldehyde greater than 12 hours may reduce hybridization efficiency.

This test was developed, and its performance characteristics determined, by LabCorp. It has not been cleared or approved by the US Food and Drug Administration (FDA). The FDA has determined that such clearance or approval is not necessary.

Specimen Requirements

Specimen

Formalin/bone marrow-fixed (not decalcified); paraffin-embedded tissue or six 4-micron to 5-micron thick section slides

Volume

One paraffin block or six 4-micron to 5-micron thick section slides

Minimum Volume

Partial paraffin block to make several slides/probe

Container

Paraffin block transport pouch

Collection Instructions

Specimen should be fixed in 10% neutral-buffered formalin or formaldehyde.

Storage Instructions

Maintain specimen at room temperature.

Causes for Rejection

Improperly embedded prep; poor fixation <6 hours and >72 hours; decalcified bone or bone core; broken or dirty slides; absence of tumor or quantity not sufficient for analysis

LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
510825 FISH Paraffin Block Test 510826 Specimen Type 31208-2
510825 FISH Paraffin Block Test 510827 Cells Counted 62361-1
510825 FISH Paraffin Block Test 510828 Cells Analyzed 62360-3
510825 FISH Paraffin Block Test 510829 FISH Result 59267-5
510825 FISH Paraffin Block Test 510831 Interpretation 50398-7
510825 FISH Paraffin Block Test 510832 Director Review: 48672-0
510825 FISH Paraffin Block Test 512123 PDF 11502-2
Order Code510825
Order Code NameFISH Paraffin Block Test
Order Loinc
Result Code510826
Result Code NameSpecimen Type
UofM
Result LOINC31208-2
Order Code510825
Order Code NameFISH Paraffin Block Test
Order Loinc
Result Code510827
Result Code NameCells Counted
UofM
Result LOINC62361-1
Order Code510825
Order Code NameFISH Paraffin Block Test
Order Loinc
Result Code510828
Result Code NameCells Analyzed
UofM
Result LOINC62360-3
Order Code510825
Order Code NameFISH Paraffin Block Test
Order Loinc
Result Code510829
Result Code NameFISH Result
UofM
Result LOINC59267-5
Order Code510825
Order Code NameFISH Paraffin Block Test
Order Loinc
Result Code510831
Result Code NameInterpretation
UofM
Result LOINC50398-7
Order Code510825
Order Code NameFISH Paraffin Block Test
Order Loinc
Result Code510832
Result Code NameDirector Review:
UofM
Result LOINC48672-0
Order Code510825
Order Code NameFISH Paraffin Block Test
Order Loinc
Result Code512123
Result Code NamePDF
UofM
Result LOINC11502-2