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Fluorescence in situ Hybridization (FISH), Paraffin Block
CPT:
Contact CPT coding department at 800-222-7566, ext 6-8400.
Synonyms
- Cytogenetics Fluorescence in situ Hybridization on Paraffin-embedded Tissue
Special Instructions
This test number is used for tracking FISH paraffin samples to the testing facility. Billing will occur after testing is completed.
Pertinent medical findings and probe desired must accompany request for FISH. If prior chromosome analysis has been performed, include a copy of the report. Please direct questions to genetics customer service at 800-345-4363.
Expected Turnaround Time
5 - 7 days
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
Related Information
Related Documents
Specimen Requirements
Specimen
Formalin/bone marrow-fixed (not decalcified); paraffin-embedded tissue or six 4-micron to 5-micron thick section slides
Volume
One paraffin block or six 4-micron to 5-micron thick section slides
Minimum Volume
Partial paraffin block to make several slides/probe
Container
Paraffin block transport pouch
Collection
Specimen should be fixed in 10% neutral-buffered formalin or formaldehyde.
Storage Instructions
Maintain specimen at room temperature.
Causes for Rejection
Improperly embedded prep; poor fixation <6 hours and >72 hours; decalcified bone or bone core; broken or dirty slides; absence of tumor or quantity not sufficient for analysis
Test Details
Use
For specific FISH probe analysis of tissue specimens
Limitations
Samples in formaldehyde greater than 12 hours may reduce hybridization efficiency.
This test was developed, and its performance characteristics determined, by LabCorp. It has not been cleared or approved by the US Food and Drug Administration (FDA). The FDA has determined that such clearance or approval is not necessary.
Methodology
Fluorescence in situ hybridization (FISH) from formalin-fixed tissue-embedded paraffin (4-micron to 5-micron sections); H&E for pathology review.
LOINC® Map
| Order Code | Order Code Name | Order Loinc | Result Code | Result Code Name | UofM | Result LOINC |
|---|---|---|---|---|---|---|
| 510825 | FISH Paraffin Block Test | 510826 | Specimen Type | 31208-2 | ||
| 510825 | FISH Paraffin Block Test | 510827 | Cells Counted | 62361-1 | ||
| 510825 | FISH Paraffin Block Test | 510828 | Cells Analyzed | 62360-3 | ||
| 510825 | FISH Paraffin Block Test | 510829 | FISH Result | 59267-5 | ||
| 510825 | FISH Paraffin Block Test | 510831 | Interpretation | 50398-7 | ||
| 510825 | FISH Paraffin Block Test | 510832 | Director Review: | 48672-0 | ||
| 510825 | FISH Paraffin Block Test | 512123 | 51967-8 |
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The LOINC® codes are copyright © 1994-2021, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. Permission is granted in perpetuity, without payment of license fees or royalties, to use, copy, or distribute the LOINC® codes for any commercial or non-commercial purpose, subject to the terms under the license agreement found at https://loinc.org/license/. Additional information regarding LOINC® codes can be found at LOINC.org, including the LOINC Manual, which can be downloaded at LOINC.org/downloads/files/LOINCManual.pdf