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Fluorescence in situ Hybridization (FISH), Oncology
CPT:
Contact CPT coding department at 800-222-7566, ext 6-8400.
Special Instructions
Call for additional probes not listed above. Pertinent clinical diagnosis, previous cytogenetic studies, and probe of interest should be included with the specimen (Call for a list of available probes or see online list.).
This test number is used for tracking oncology FISH specimens to the laboratory. Bill codes will be added when testing is complete, based on the processes performed in the laboratory.
Please provide targeted FISH probe and diagnosis. This test is essentially a tracking code, and the test will only be performed after the probes and diagnosis is provided. Absence of this information will delay turnaround time.
Expected Turnaround Time
3 - 5 days
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
Related Information
- BCR-ABL1 Transcript Detection for Chronic Myelogenous Leukemia (CML) and Acute Lymphocytic Leukemia (ALL), Quantitative
- PML-RARA Transcript Detection for Acute Promyelocytic Leukemia, Quantitative
- Fluorescence in situ Hybridization (FISH), Paraffin Block
- Oncology Fluorescence in situ Hybridization (FISH)
Related Documents
Specimen Requirements
Specimen
Fixed-cell pellet from a cytogenetic analysis, slides with metaphases and/or interphase nuclei, or bone marrow touch prep slides. Blood, bone marrow, cerebrospinal fluid (CSF), FNA are also acceptable.
Volume
Fixed-cell pellet, three slides, 10 mL blood (adult), 5 mL blood (pediatric), or 3 mL bone marrow
Minimum Volume
Fixed-cell pellet from a cytogenetic analysis, two slides, 5 mL blood (adult), 1 mL blood (pediatric), or 1 mL bone marrow
Container
Green-top (heparin) tube; pediatric Vacutainer® is optimal or lavender-top (EDTA) tube
Collection
Transport to the testing lab at room temperature; use a cool pack or LabCorp transport kit. Do not allow the sample to freeze.
Storage Instructions
Maintain specimen at room temperature.
Causes for Rejection
Broken or dirty slides; excessive cellular debris or stained slides; frozen specimen
Test Details
Use
Confirmation/identification of leukemia/lymphoma-related alterations; leukemia/lymphoma monitoring of residual disease, transplants, and indolent clones (see list or call lab for probe availability).
Methodology
Fluorescence in situ hybridization (FISH)
LOINC® Map
| Order Code | Order Code Name | Order Loinc | Result Code | Result Code Name | UofM | Result LOINC |
|---|---|---|---|---|---|---|
| 510669 | FISH Oncology | 510670 | Specimen Type | 31208-2 | ||
| 510669 | FISH Oncology | 510671 | Cells Counted | 62361-1 | ||
| 510669 | FISH Oncology | 510672 | Cells Analyzed | 62360-3 | ||
| 510669 | FISH Oncology | 510673 | FISH Result | 62356-1 | ||
| 510669 | FISH Oncology | 510674 | Interpretation | 62365-2 | ||
| 510669 | FISH Oncology | 510638 | Director Review: | 48672-0 | ||
| 510669 | FISH Oncology | 512123 | 51967-8 |
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CPT Statement/Profile Statement
The LOINC® codes are copyright © 1994-2021, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. Permission is granted in perpetuity, without payment of license fees or royalties, to use, copy, or distribute the LOINC® codes for any commercial or non-commercial purpose, subject to the terms under the license agreement found at https://loinc.org/license/. Additional information regarding LOINC® codes can be found at LOINC.org, including the LOINC Manual, which can be downloaded at LOINC.org/downloads/files/LOINCManual.pdf