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Special Instructions
State the patient's sex on the test request form.
Expected Turnaround Time
3 - 6 days
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
Related Documents
Specimen Requirements
Specimen
Serum, frozen
Volume
1 mL
Minimum Volume
0.5 mL
Container
Red-top tube
Collection
Separate serum from red cells. To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested.
Storage Instructions
Freeze
Causes for Rejection
Hemolysis; specimen not frozen
Test Details
Use
Serum creatine levels may be significantly increased in amyotrophic lateral sclerosis, dermatomyositis, myasthenia gravis, starvation, muscular dystrophies, and trauma. Creatine synthesis is stimulated by methyltestosterone and may also be increased in hyperthyroidism, diabetic acidosis, and puerperium.
Methodology
Enzymatic (creatinase)/spectrophotometry
Reference Interval
See table.
Age (y) | Range (mg/dL) |
|---|---|
0−1 | 0.1−1.4 |
2−5 | 0.6−1.4 |
6−9 | 0.5−1.3 |
10−13 | 0.2−1.1 |
14−17 | 0.0−0.8 |
Female: >17 | 0.1−1.0 |
Male: >17 | 0.0−0.7 |
Additional Information
Creatine is transported from the sites of synthesis (kidney, liver, pancreas) via the circulatory system to muscle and brain tissue where it is phosphorylated to phosphocreatine. Phosphocreatine and creatine are rapidly interconverted during muscle contraction. Approximately 1% to 2% of free creatine in muscle is converted to creatinine daily.
LOINC® Map
| Order Code | Order Code Name | Order Loinc | Result Code | Result Code Name | UofM | Result LOINC |
|---|---|---|---|---|---|---|
| 002402 | Creatine, Serum | 2148-5 | 002402 | Creatine, Serum | mg/dL | 2148-5 |
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CPT Statement/Profile Statement
The LOINC® codes are copyright © 1994-2021, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. Permission is granted in perpetuity, without payment of license fees or royalties, to use, copy, or distribute the LOINC® codes for any commercial or non-commercial purpose, subject to the terms under the license agreement found at https://loinc.org/license/. Additional information regarding LOINC® codes can be found at LOINC.org, including the LOINC Manual, which can be downloaded at LOINC.org/downloads/files/LOINCManual.pdf