Find Locations
For hours, walk-ins and appointments.Synonyms
- Cr, Urine
Test Includes
Chromium, urine; creatinine, urine; chromium:creatinine ratio
Special Instructions
Do not use preservative. Preservatives used for routine analysis may contain mercuric oxide (ie, Stabilur), which interferes with all metal testing. If both urinalysis and metal testing are ordered, please submit a separate urine specimen (containing no additive) for the metal testing.
Expected Turnaround Time
2 - 4 days
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
Related Information
Related Documents
Specimen Requirements
Specimen
Urine (random)
Volume
5 mL
Minimum Volume
0.6 mL
Container
Plastic urine container, no preservative
Collection
Sampling time is during shift or at the end of shift at the end of the work week for industrial exposure monitoring. For metals with multiphase elimination, the timing is given in relation to the work day exposure (shift) as well as to the work week exposure.
Storage Instructions
Maintain specimen at room temperature.
Stability Requirements
Temperature | Period |
|---|---|
Room temperature | 14 days |
Refrigerated | 14 days |
Frozen | 14 days |
Freeze/thaw cycles | Stable x3 |
Test Details
Use
Monitor industrial exposure to chromium
Limitations
This test was developed and its performance characteristics determined by LabCorp. It has not been cleared or approved by the Food and Drug Administration.
Methodology
Inductively-coupled plasma/mass spectrometry (ICP/MS)
Reference Interval
Occupational exposure: BEI® (sampling time is during shift): 10.0 μg/L;1 BEI® (sampling time is end of shift at the end of the work week): 25.0 μg/L1
Additional Information
Chromium exposure through the inhalation of insoluble chromium compounds may produce pneumoconiosis with impairment of pulmonary function. Exposure to the inorganic soluble salts can precipitate skin ulcerations, dermatitis, perforation of the nasal septum, and respiratory sensitization. Acute exposure to these salts may result in local tissue necrosis and severe kidney damage.2
Chromium and its inorganic salts are widely employed in industry, including metal plating, steel and nonferrous alloys, refractory materials, and chromate pigments and preservatives. In organic forms, chromium is also an essential nutrient for man supplied in the diet (5−115 μg/day); however, overexposure is generally associated with the industrial environment, specifically through the inhalation of chromium dust and fumes.
BEI® are reference values intended as guidelines for evaluation of occupational exposure. BEI® represent biological levels of chemicals that correspond to workers with inhalation exposure equivalent to the threshold limit value (TLV®) of the chemicals. TLVs refer to the airborne concentrations of substances and represent conditions under which it is believed that nearly all workers may be repeatedly exposed, day after day, without adverse health effects.3
Footnotes
1. BEI® (Biological Exposure Indices) based on 2010 Recommendations of the American Conference of Governmental Industrial Hygienists (ACGIH).
2. Baselt RC, Cravey RH. Disposition of Toxic Drugs and Chemicals in Man. 4th ed. Chemical Toxicology Institute;1995.
3. TLVs and BEIs, Threshold Limit Values for Chemical Substances and Physical Agents and Biological Exposure Indices 2010, American Conference of Governmental Industrial Hygienists (ACGIH).
LOINC® Map
| Order Code | Order Code Name | Order Loinc | Result Code | Result Code Name | UofM | Result LOINC |
|---|---|---|---|---|---|---|
| 071530 | Chromium, Urine | 13464-3 | 071535 | Chromium, Urine | ug/L | 5623-4 |
| 071530 | Chromium, Urine | 13464-3 | 723280 | Creatinine(Crt),U | g/L | 2161-8 |
| 071530 | Chromium, Urine | 13464-3 | 071511 | Chromium/Creat Ratio | ug/g creat | 13464-3 |
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The LOINC® codes are copyright © 1994-2021, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. Permission is granted in perpetuity, without payment of license fees or royalties, to use, copy, or distribute the LOINC® codes for any commercial or non-commercial purpose, subject to the terms under the license agreement found at https://loinc.org/license/. Additional information regarding LOINC® codes can be found at LOINC.org, including the LOINC Manual, which can be downloaded at LOINC.org/downloads/files/LOINCManual.pdf