Test Details
Methodology
Immunochemiluminometric assay (ICMA)
Result Turnaround Time
3 - 4 days
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
Use
Evaluate renal disease; monitor certain types of malignancies and AIDS
Limitations
This test has not been validated for the measurement of osmolality of fetal urine.
Specimen Requirements
Specimen
Urine (random)
Volume
10 mL
Minimum Volume
1 mL (Note: This volume does not allow for repeat testing.)
Container
Plastic urine container (do not acidify)
Collection Instructions
Patient should empty the bladder, then drink a large glass of water and collect a urine sample within one hour. Significant loss of β2-microglobulin activity may occur in acidic urine (pH ≤6). Urine should always be collected at high diuresis and the pH adjusted to between 6 and 8 with 1 mol/L sodium hydroxide.
Stability Requirements
| Temperature | Period |
|---|---|
| Room temperature | 7 days |
| Refrigerated | 7 days |
| Frozen | 14 days |
| Freeze/thaw cycles | Stable x3 |
Reference Range
0−300 μg/L
Storage Instructions
Refrigerate.
Causes for Rejection
Fetal urine sample received
LOINC® Map
| Order Code | Order Code Name | Order Loinc | Result Code | Result Code Name | UofM | Result LOINC |
|---|---|---|---|---|---|---|
| 010173 | Beta-2 Microglobulin, Urine | 1953-9 | 010173 | Beta-2 Microglobulin, Urine | ug/L | 1953-9 |
| Order Code | 010173 | |||||
| Order Code Name | Beta-2 Microglobulin, Urine | |||||
| Order Loinc | 1953-9 | |||||
| Result Code | 010173 | |||||
| Result Code Name | Beta-2 Microglobulin, Urine | |||||
| UofM | ug/L | |||||
| Result LOINC | 1953-9 |