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Synonyms
- ALL FISH
- CML FISH
Special Instructions
Pertinent clinical diagnosis, previous cytogenetic studies, and probe of interest should be included with the specimen. Please provide targeted FISH probe and diagnosis.
Expected Turnaround Time
3 - 5 days
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
Related Information
Related Documents
Specimen Requirements
Specimen
Fixed-cell pellet from a cytogenetic analysis, slides with metaphases and/or interphase nuclei or bone marrow touch prep slides. Blood, bone marrow, cerebrospinal fluid (CSF).
Volume
Fixed-cell pellet, three slides, 10 mL blood (adult), 5 mL blood (pediatric), or 3 mL bone marrow
Minimum Volume
Fixed-cell pellet from a cytogenetic analysis, two slides, 5 mL blood (adult), 1 mL blood (pediatric), or 1 mL bone marrow
Container
Green-top (heparin) tube, pediatric Vacutainer® (optimal), or lavender-top (EDTA) tube
Collection
Transport to the testing lab at room temperature; LabCorp transport kit. Do not allow sample to overheat or freeze.
Storage Instructions
Maintain specimen at room temperature.
Causes for Rejection
Broken or dirty slides; excessive cellular debris or stained slides/paraffin blocks; decalcified bone cores; frozen specimen
Test Details
Use
Confirmation/identification of leukemia/lymphoma-related alterations; leukemia/lymphoma monitoring of residual disease.
Methodology
Fluorescence in situ hybridization (FISH)
LOINC® Map
| Order Code | Order Code Name | Order Loinc | Result Code | Result Code Name | UofM | Result LOINC |
|---|---|---|---|---|---|---|
| 511520 | Oncology BCR/ABL1 FISH | 511504 | Specimen Type | 31208-2 | ||
| 511520 | Oncology BCR/ABL1 FISH | 511505 | Cells Counted | 62361-1 | ||
| 511520 | Oncology BCR/ABL1 FISH | 511506 | Cells Analyzed | 62360-3 | ||
| 511520 | Oncology BCR/ABL1 FISH | 511507 | FISH Result | 62356-1 | ||
| 511520 | Oncology BCR/ABL1 FISH | 511508 | Interpretation | 62365-2 | ||
| 511520 | Oncology BCR/ABL1 FISH | 511509 | Director Review: | 48672-0 | ||
| 511520 | Oncology BCR/ABL1 FISH | 512123 | 51967-8 |
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CPT Statement/Profile Statement
The LOINC® codes are copyright © 1994-2021, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. Permission is granted in perpetuity, without payment of license fees or royalties, to use, copy, or distribute the LOINC® codes for any commercial or non-commercial purpose, subject to the terms under the license agreement found at https://loinc.org/license/. Additional information regarding LOINC® codes can be found at LOINC.org, including the LOINC Manual, which can be downloaded at LOINC.org/downloads/files/LOINCManual.pdf