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For hours, walk-ins and appointments.Synonyms
- Rochalimaea
- Bacillary Angiomatosis (BA)
- Cat Scratch Disease Antibody
Test Includes
Bartonella henselae, IgG; Bartonella henselae, IgM; Bartonella quintana, IgG; Bartonella quintana, IgM
Expected Turnaround Time
1 - 5 days
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
Related Documents
Specimen Requirements
Specimen
Serum
Volume
2 mL
Minimum Volume
0.3 mL (Note: This volume does not allow for repeat testing.)
Container
Red-top tube or gel-barrier tube
Storage Instructions
Room temperature
Stability Requirements
Temperature | Period |
|---|---|
Room temperature | 14 days |
Refrigerated | 14 days |
Frozen | 14 days |
Freeze/thaw cycles | Stable x3 |
Causes for Rejection
Hemolysis; lipemia; gross bacterial contamination
Test Details
Use
Bartonella (formerly Rochalimaea) henselae has become firmly established as the primary etiologic agent for cat scratch disease (CSD). Bartonella quintana, known for some time as a cause of trench fever, is also associated with CSD and bacillary angiomatosis (BA). Both diseases frequently affect immunocompromised patients, particularly those infected with HIV-1. Although CSD is generally a self-limiting disease, it can be life-threatening.
Limitations
There is some cross-reactivity between the IgG classes of B. henselae and B. quintana.
This test was developed and its performance characteristics determined by Labcorp. It has not been cleared or approved by the Food and Drug Administration. The FDA has determined that such clearance or approval is not necessary.
Methodology
Indirect fluorescent antibody (IFA)
References
Anderson BE, Neuman MA. Bartonella spp as emerging human pathogens. Clin Microbiol Rev. 1997 Apr; 10(2):203-219. 9105751
Chomel BB, Abbott RC, Kasten RW, et al. Bartonella henselae prevalence in domestic cats in California: Risk factors and association between bacteremia and antibody titers. J Clin Microbiol. 1995 Sep; 33(9):2445-2450. 7494043
Regnery RL, Anderson BE, Clarridge JE 3rd, Rodríguez-Barradas MC, Jones DC, Carr JH. Characterization of a novel Rochalimaea species, R. henselae sp. nov., isolated from blood of a febrile, human immunodeficiency virus-positive patient. J Clin Microbiol. 1992 Feb; 30(2):265-274. 1371515
Regnery R, Tappero J. Unraveling mysteries associated with cat-scratch disease, bacillary angiomatosis, and related syndromes. Emerg Infect Dis. 1995 Jan-Mar; 1(1):16-21. 8903149
Sander A, Posselt M, Oberle K, Bredt W. Seroprevalence of antibodies to Bartonella henselae in patients with cat scratch disease and in healthy controls: Evaluation and comparison of two commercial serological tests. Clin Diagn Lab Immunol. 1998 Jul; 5(4):486-490. 9665953
Welch DF, Pickett DA, Slater LN, Steigerwalt AG, Brenner DJ. Rochalimaea sp. nov., a cause of septicemia, bacillary angiomatosis, and parenchymal bacillary peliosis. J Clin Microbiol. 1992 Feb; 30(2):275-280. 1537892
LOINC® Map
| Order Code | Order Code Name | Order Loinc | Result Code | Result Code Name | UofM | Result LOINC |
|---|---|---|---|---|---|---|
| 163162 | Bartonella Antibody Panel | 90251-0 | 163163 | B. henselae IgG | titer | 6954-2 |
| 163162 | Bartonella Antibody Panel | 90251-0 | 163164 | B. henselae IgM | titer | 6955-9 |
| 163162 | Bartonella Antibody Panel | 90251-0 | 163165 | B. quintana IgG | titer | 44827-4 |
| 163162 | Bartonella Antibody Panel | 90251-0 | 163168 | B. quintana IgM | titer | 44825-8 |
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