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Antiparietal Cell Antibody (APCA)

CPT 83516
Synonyms
  • Gastric Parietal Cell Antibodies

Test Details

Methodology

Enzyme-linked immunosorbent assay (ELISA)

Result Turnaround Time

2 - 4 days

Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.

Related Information

Related Documents

Test Includes

Titer

Use

Detection of gastric parietal cell antibodies of the IgG class in human sera. Autoantibodies to gastric parietal cells are found in approximately 90% of patients with pernicious anemia and in about 30% of first degree relatives of patients with pernicious anemia. Increased levels of gastric parietal cells have been found in patients with thyroid disease, iron deficiency anemia, alopecia areata, and vitiligo.

Limitations

The presence of immune complexes in a patient's sample may cause an elevated level of nonspecific binding and produce false-positive results. Assay performance has not been established for pediatric patients.

Specimen Requirements

Specimen

Serum

Volume

1 mL

Minimum Volume

0.3 mL

Container

Red-top tube or gel-barrier tube

Stability Requirements

Temperature

Period

Room temperature

14 days

Refrigerated

14 days

Frozen

14 days

Freeze/thaw cycles

Stable x3

Reference Range

• Negative: 0.0−20.0

• Equivocal: 20.1−24.9

• Positive: >24.9

Storage Instructions

Room temperature

Causes for Rejection

Hemolysis; lipemia; gross bacterial contamination; heat-treated specimen; specimen with preservative added

LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
006486 Antiparietal Cell Antibody 8087-9 006487 Antiparietal Cell Antibody Units 8087-9
Order Code006486
Order Code NameAntiparietal Cell Antibody
Order Loinc8087-9
Result Code006487
Result Code NameAntiparietal Cell Antibody
UofMUnits
Result LOINC8087-9