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Synonyms
- Gastric Parietal Cell Antibodies
Test Includes
Titer
Expected Turnaround Time
2 - 4 days
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
Related Information
Related Documents
Specimen Requirements
Specimen
Serum
Volume
1 mL
Minimum Volume
0.3 mL
Container
Red-top tube or gel-barrier tube
Storage Instructions
Room temperature
Stability Requirements
Temperature | Period |
|---|---|
Room temperature | 14 days |
Refrigerated | 14 days |
Frozen | 14 days |
Freeze/thaw cycles | Stable x3 |
Causes for Rejection
Hemolysis; lipemia; gross bacterial contamination; heat-treated specimen; specimen with preservative added
Test Details
Use
Detection of gastric parietal cell antibodies of the IgG class in human sera. Autoantibodies to gastric parietal cells are found in approximately 90% of patients with pernicious anemia and in about 30% of first degree relatives of patients with pernicious anemia. Increased levels of gastric parietal cells have been found in patients with thyroid disease, iron deficiency anemia, alopecia areata, and vitiligo.
Limitations
The presence of immune complexes in a patient's sample may cause an elevated level of nonspecific binding and produce false-positive results. Assay performance has not been established for pediatric patients.
Methodology
Enzyme-linked immunosorbent assay (ELISA)
Reference Interval
• Negative: 0.0−20.0
• Equivocal: 20.1−24.9
• Positive: >24.9
LOINC® Map
| Order Code | Order Code Name | Order Loinc | Result Code | Result Code Name | UofM | Result LOINC |
|---|---|---|---|---|---|---|
| 006486 | Antiparietal Cell Antibody | 8087-9 | 006487 | Antiparietal Cell Antibody | Units | 8087-9 |
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CPT Statement/Profile Statement
The LOINC® codes are copyright © 1994-2021, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. Permission is granted in perpetuity, without payment of license fees or royalties, to use, copy, or distribute the LOINC® codes for any commercial or non-commercial purpose, subject to the terms under the license agreement found at https://loinc.org/license/. Additional information regarding LOINC® codes can be found at LOINC.org, including the LOINC Manual, which can be downloaded at LOINC.org/downloads/files/LOINCManual.pdf