Allergen Profile, Food, IgE With Component Reflexes

TEST: 608005
Test number copied
CPT: 86003(x16); 86008
Print Share

Test Includes

This profile includes total IgE, the nine major allergen groups associated with food allergy,1-4 and their reflexes to components: almond; Brazil nut; cashew nut; codfish; egg white; hazelnut (filbert); milk; peanut (whole); salmon; scallop; sesame seed; shrimp; soybean; tuna; walnut; wheat; and w5-gliadin (tri-19).

• If milk IgE ≥ 0.35 kU/L, reflex tests α-lactalbumin, β-lactoglobulin and casein will be added.

• If egg white IgE ≥ 0.35 kU/L, reflex tests ovalbumin and ovomucoid will be added.

• If sesame IgE ≥ 0.10 kU/L, reflex test Ses I 1 will be added.

• If walnut IgE ≥ 0.10 kU/L, reflex tests Jug r 1 and Jug r 3 will be added.

• If hazelnut (filbert) IgE ≥ 0.10 kU/L, reflex tests Cor a 1, Cor a 8, Cor a 9 and Cor a 14 will be added.

• If cashew nut IgE ≥ 0.10 kU/L, reflex test Ana o 3 will be added.

• If Brazil nut IgE ≥ 0.10 kU/L, reflex test Ber e 1 will be added.

• If peanut (whole) IgE ≥0.10 kU/L, reflex tests Ara h 1, Ara h 2, Ara h 3, Ara h 6, Ara h 8 and Ara h 9 will be added.

• If wheat IgE ≥ 0.10 kU/L, one or more of the following components may be tested: Gliadin, Tri a 14 (wheat nsLTP), Phl p 12 (Timothy grass profilin) and/or Cross-reactive Carbohydrate Determinant (CCD).

Expected Turnaround Time

3 - 5 days

Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.

Related Information

Related Documents

For more information, please view the literature below.

Food Allergy Testing Brochure

Specimen Requirements

Specimen

Serum

Volume

4 mL

Minimum Volume

3 mL (Note: This volume does not allow for repeat testing.)

Container

Red-top tube or gel-barrier tube

Collection

If a red-top tube is used, transfer separated serum to a plastic transport tube.

Storage Instructions

Room temperature

Stability Requirements

Temperature

Period

Room temperature

14 days

Refrigerated

14 days

Frozen

3 months

Freeze/thaw cycles

Stable x3

Test Details

Use

This panel is designed to measure the extent of allergen sensitization in children, adolescents and adults.

Methodology

Thermo Fisher ImmunoCAP® Allergen-specific IgE

Footnotes

1. Sicherer SH, Warren CM, Dant C, Gupta RS, Nadeau KC. Food Allergy from Infancy Through Adulthood. J Allergy Clin Immunol Pract. 2020 Jun;8(6):1854-1864.32499034
2. Major Allergens: The Big Nine. School Nutrition Association (SNA) website: https://schoolnutrition.org/resource/major-allergens-the-big-nine/. Accessed January 2024.
3. Food Allergies. U.S. Food and Drug Administration website: https://www.fda.gov/food/food-labeling-nutrition/food-allergies. Accessed January 2024.
4. Food Allergy & Anaphylaxis. Food Allergy and Anaphylaxis Connection Team website: https://www.foodallergyawareness.org/food-allergy-and-anaphylaxis/food-allergens/the-top-9-foodallergens/. Accessed January 2024.

References

Gupta RS, Warren CM, Smith BM, et al. Prevalence and Severite of Food Allergies Among US Adults. JAMA Netw Open. 2019 Jan 4;2(1):e185630.30646188
Gupta RS, Warren CM, Smith BM, et al. The Public Health Impact of Parent-Reported Childhood Food Allergies in the United States. Pediatrics. 2018 Dec;142(6):e20181235.30455345
Savage J, Sicherer S, Wood R. The Natural History of Food Allergy. J Allergy Clin Immunol Pract. 2016 Mar-Apr;4(2):196-203; quiz 204.26968958
Sicherer SH, Sampson HA. Food allergy: A review and update on epidemiology, pathogenesis, diagnosis, prevention, and management. J Allergy Clin Immunol. 2018 Jan;141(1):41-58.29157945
Sicherer SH, Sampson HA. Food allergy: Epidemiology, pathogenesis, diagnosis, and treatment. J Allergy Clin Immunol. 2014 Feb;133(2):291-307; quiz 308.24388012

LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
608005 Allergy Profile, Food 602444 Class Description N/A
608005 Allergy Profile, Food 602457 F014-IgE Soybean kU/L 6248-9
608005 Allergy Profile, Food 602479 F020-IgE Almond kU/L 6019-4
608005 Allergy Profile, Food 602465 F003-IgE Codfish kU/L 6082-2
608005 Allergy Profile, Food 602507 F041-IgE Salmon kU/L 6237-2
608005 Allergy Profile, Food 602510 F040-IgE Tuna kU/L 6270-3
608005 Allergy Profile, Food 602478 F338-IgE Scallop kU/L 7691-9
608005 Allergy Profile, Food 602473 F024-IgE Shrimp kU/L 6246-3
608005 Allergy Profile, Food 606844 F002-IgE Milk kU/L 7258-7
608005 Allergy Profile, Food 606841 F001-IgE Egg White kU/L 6106-9
608005 Allergy Profile, Food 607741 F010-IgE Sesame Seed kU/L 6242-2
608005 Allergy Profile, Food 606414 F013-IgE Peanut kU/L 6206-7
608005 Allergy Profile, Food 606842 F017-IgE Hazelnut (Filbert) kU/L 6136-6
608005 Allergy Profile, Food 606845 F256-IgE Walnut kU/L 6273-7
608005 Allergy Profile, Food 606837 F202-IgE Cashew Nut kU/L 6718-1
608005 Allergy Profile, Food 606836 F018-IgE Brazil Nut kU/L 6050-9
608005 Allergy Profile, Food 607843 F416-IgE Tri a 19(w-5 gliadin) kU/L 58752-7
608005 Allergy Profile, Food 607841 F004-IgE Wheat kU/L 6276-0
608005 Allergy Profile, Food 607999 Reflex N/A
Reflex Table for F002-IgE Milk
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 603848 Panel 603848 602731 F076-IgE Alpha Lactalbumin kU/L 7445-0
Reflex Table for F002-IgE Milk
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 603848 Panel 603848 602505 F077-IgE Beta Lactoglobulin kU/L 41397-1
Reflex Table for F002-IgE Milk
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 603848 Panel 603848 602554 F078-IgE Casein kU/L 6062-4
Reflex Table for F001-IgE Egg White
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 603851 Panel 603851 602791 F232-IgE Ovalbumin kU/L 7556-4
Reflex Table for F001-IgE Egg White
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 603851 Panel 603851 602792 F233-IgE Ovomucoid kU/L 7557-2
Reflex Table for F010-IgE Sesame Seed
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 607742 F449-IgE Ses i 1 607742 F449-IgE Ses i 1 kU/L Pending
Reflex Table for F013-IgE Peanut
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 604845 Panel 604845 603835 F422-IgE Ara h 1 kU/L 58779-0
Reflex Table for F013-IgE Peanut
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 604845 Panel 604845 603836 F423-IgE Ara h 2 kU/L 58778-2
Reflex Table for F013-IgE Peanut
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 604845 Panel 604845 603838 F424-IgE Ara h 3 kU/L 58777-4
Reflex Table for F013-IgE Peanut
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 604845 Panel 604845 605970 F447-IgE Ara h 6 kU/L 90880-6
Reflex Table for F013-IgE Peanut
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 604845 Panel 604845 603839 F352-IgE Ara h 8 kU/L 63477-4
Reflex Table for F013-IgE Peanut
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 604845 Panel 604845 603840 F427-IgE Ara h 9 kU/L 64965-7
Reflex Table for F017-IgE Hazelnut (Filbert)
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 604726 Panel 604726 604735 F428-IgE Cor a 1 kU/L 69421-6
Reflex Table for F017-IgE Hazelnut (Filbert)
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 604726 Panel 604726 604741 F425-IgE Cor a 8 kU/L 58753-5
Reflex Table for F017-IgE Hazelnut (Filbert)
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 604726 Panel 604726 604742 F440-IgE Cor a 9 kU/L 65765-0
Reflex Table for F017-IgE Hazelnut (Filbert)
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 604726 Panel 604726 604743 F439-IgE Cor a 14 kU/L 81788-2
Reflex Table for F256-IgE Walnut
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 604721 Panel 604721 604719 F441-IgE Jug r 1 kU/L 81790-8
Reflex Table for F256-IgE Walnut
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 604721 Panel 604721 604720 F442-IgE Jug r 3 kU/L 81789-0
Reflex Table for F202-IgE Cashew Nut
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 604239 Panel 604239 604161 F443-IgE Ana o 3 kU/L 82539-8
Reflex Table for F018-IgE Brazil Nut
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 604350 Panel 604350 604158 F354-IgE Ber e 1 kU/L 64963-2
Reflex Table for Reflex
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 607953 F098-IgE Gliadin, Wheat 602444 Class Description N/A
Reflex Table for Reflex
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 607953 F098-IgE Gliadin, Wheat 607842 F098-IgE Gliadin, Wheat kU/L 82583-6
Reflex Table for Reflex
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 607953 F098-IgE Gliadin, Wheat 607956 Reflex N/A
Reflex 2 607954 F433-IgE Tri a 14 (nsLTP) 602444 Class Description N/A
Reflex Table for Reflex
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 607953 F098-IgE Gliadin, Wheat 607956 Reflex N/A
Reflex 2 607954 F433-IgE Tri a 14 (nsLTP) 607844 F433-IgE Tri a 14 (nsLTP) kU/L 64966-5
Reflex Table for Reflex
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 607953 F098-IgE Gliadin, Wheat 607956 Reflex N/A
Reflex 2 607954 F433-IgE Tri a 14 (nsLTP) 607951 Reflex N/A
Reflex 3 607957 G212-IgE Phl p 12 (Profilin) 602444 Class Description N/A
Reflex Table for Reflex
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 607953 F098-IgE Gliadin, Wheat 607956 Reflex N/A
Reflex 2 607954 F433-IgE Tri a 14 (nsLTP) 607951 Reflex N/A
Reflex 3 607957 G212-IgE Phl p 12 (Profilin) 607845 G212-IgE Phl p 12 (Profilin) kU/L 34428-3
Reflex Table for Reflex
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 607953 F098-IgE Gliadin, Wheat 607956 Reflex N/A
Reflex 2 607954 F433-IgE Tri a 14 (nsLTP) 607951 Reflex N/A
Reflex 3 607957 G212-IgE Phl p 12 (Profilin) 607958 Reflex N/A
Reflex 4 607959 O214-IgE CCD Determinants 602444 Class Description N/A
Reflex Table for Reflex
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 607953 F098-IgE Gliadin, Wheat 607956 Reflex N/A
Reflex 2 607954 F433-IgE Tri a 14 (nsLTP) 607951 Reflex N/A
Reflex 3 607957 G212-IgE Phl p 12 (Profilin) 607958 Reflex N/A
Reflex 4 607959 O214-IgE CCD Determinants 606381 O214-IgE CCD Determinants kU/L 58984-6
Reflex Table for Reflex
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 607953 F098-IgE Gliadin, Wheat 607956 Reflex N/A
Reflex 2 607954 F433-IgE Tri a 14 (nsLTP) 607951 Reflex N/A
Reflex 3 607957 G212-IgE Phl p 12 (Profilin) 607958 Reflex N/A
Reflex 4 607959 O214-IgE CCD Determinants 606381 O214-IgE CCD Determinants kU/L 58984-6
Reflex 5 607851 Reflex to Litholink 607851 Reflex to Litholink N/A
Reflex Table for Reflex
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 607953 F098-IgE Gliadin, Wheat 607956 Reflex N/A
Reflex 2 607954 F433-IgE Tri a 14 (nsLTP) 607951 Reflex N/A
Reflex 3 607957 G212-IgE Phl p 12 (Profilin) 607958 Reflex N/A
Reflex 4 607851 Reflex to Litholink 607851 Reflex to Litholink N/A
Reflex Table for Reflex
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 607953 F098-IgE Gliadin, Wheat 607956 Reflex N/A
Reflex 2 607954 F433-IgE Tri a 14 (nsLTP) 607951 Reflex N/A
Reflex 3 607851 Reflex to Litholink 607851 Reflex to Litholink N/A
Reflex Table for Reflex
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 607953 F098-IgE Gliadin, Wheat 607956 Reflex N/A
Reflex 2 607851 Reflex to Litholink 607851 Reflex to Litholink N/A
Reflex Table for Reflex
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 607851 Reflex to Litholink 607851 Reflex to Litholink N/A

For Providers

Please login to order a test

Order a Test

© 2021 Laboratory Corporation of America® Holdings and Lexi-Comp Inc. All Rights Reserved.

CPT Statement/Profile Statement

The LOINC® codes are copyright © 1994-2021, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. Permission is granted in perpetuity, without payment of license fees or royalties, to use, copy, or distribute the LOINC® codes for any commercial or non-commercial purpose, subject to the terms under the license agreement found at https://loinc.org/license/. Additional information regarding LOINC® codes can be found at LOINC.org, including the LOINC Manual, which can be downloaded at LOINC.org/downloads/files/LOINCManual.pdf