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CPT:
Contact CPT coding department at 800-222-7566, ext 6-8400.
Synonyms
- CVS Prenatal Karyotyping, Chromosome Analysis
Test Includes
20 mitotic cells microscopically analyzed from cultured villi and direct trophoblasts with G-banded karyotypes prepared and analyzed; ancillary direct metaphase or FISH analysis, if needed
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20 mitotic cells microscopically analyzed from cultured villi and direct trophoblasts with G-banded karyotypes prepared and analyzed |
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20 mitotic cells microscopically analyzed from cultured villi and direct trophoblasts with G-banded karyotypes prepared and analyzed; ancillary direct metaphase or FISH analysis, if needed |
Special Instructions
Pertinent medical history and test request form must accompany request for chromosome analysis. Include name, age, gestational age and indication for procedure.
If prior NIPT studies have been performed, include copy of the report.
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Pertinent medical history and test request form must accompany request for chromosome analysis. Include name, age, gestational age If prior NIPT studies have been performed, include copy of the report. |
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Pertinent medical history and test request form must accompany request for chromosome analysis. Include name, age, gestational age and indication for procedure. If prior NIPT studies have been performed, include copy of the report. |
Expected Turnaround Time
6 - 10 days
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
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6 - 10 days 6 - 10 days |
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6 - 10 days 6 - 10 days |
Related Documents
Specimen Requirements
Specimen
Chorionic villi
Volume
20 to 30 mg
Minimum Volume
5 mg
Container
The CVS transport tube (a sterile specimen container with transport medium) is available from Labcorp. Please call customer service at 800-345-4363.
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The CVS transport tube (a sterile specimen container with transport medium) is available from Labcorp. Please call customer service at 800-345-4363. |
Collection
Specimen is collected in syringe (transabdominal) or catheter (transcervical) and transferred by flushing with the media from the sterile container back into it. After collecting the specimen, wash with sterile saline solution (NaCl 0.95%) containing sodium heparin (two to three drops of sodium heparin in 10 mL of saline). Carefully transfer the specimen, into the CVS transport tube, using a sterile Pasteur pipette or a sterile fine needle forceps. Be sure to fill transport tubes completely with media. Samples from twin (multiple) pregnancies should be appropriately labeled and placed in separate transport containers with a separate request form for each twin.
Storage Instructions
Maintain specimen at room temperature and transport to the cytogenetics laboratory immediately. Do not freeze. Refrigerate if sterility is questioned or if sample cannot be shipped within 24 hours.
Causes for Rejection
No villi submitted in specimen; improper labeling; frozen specimen; specimen placed in fixative
Test Details
Use
This test is used to determine fetal karyotype.
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This test is used to determine fetal karyotype. |
Methodology
Direct harvest of trophoblasts and in situ culture from enzymatic dissociated mesenchymal cells
LOINC® Map
| Order Code | Order Code Name | Order Loinc | Result Code | Result Code Name | UofM | Result LOINC |
|---|---|---|---|---|---|---|
| 510988 | Chromosome, Chorionic Villus | 510052 | Cells Counted | 64089-6 | ||
| 510988 | Chromosome, Chorionic Villus | 510054 | Cells Analyzed | 64086-2 | ||
| 510988 | Chromosome, Chorionic Villus | 510055 | Cells Karyotyped | 64085-4 | ||
| 510988 | Chromosome, Chorionic Villus | 510056 | GTG Band Resolution | 64087-0 | ||
| 510988 | Chromosome, Chorionic Villus | 510057 | Cytogenetic Diagnosis | 33774-1 | ||
| 510988 | Chromosome, Chorionic Villus | 510989 | Cytogenetic Interpretation | 64088-8 | ||
| 510988 | Chromosome, Chorionic Villus | 510059 | Specimen Type | 31208-2 | ||
| 510988 | Chromosome, Chorionic Villus | 510991 | Director Review: | 48672-0 | ||
| 510988 | Chromosome, Chorionic Villus | 512123 | 51967-8 |
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CPT Statement/Profile Statement
The LOINC® codes are copyright © 1994-2021, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. Permission is granted in perpetuity, without payment of license fees or royalties, to use, copy, or distribute the LOINC® codes for any commercial or non-commercial purpose, subject to the terms under the license agreement found at https://loinc.org/license/. Additional information regarding LOINC® codes can be found at LOINC.org, including the LOINC Manual, which can be downloaded at LOINC.org/downloads/files/LOINCManual.pdf