Vitamin C (with Dilution)

CPT: 82180
Updated on 01/2/2025
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Synonyms

  • Ascorbic Acid
  • C, Vitamin

Special Instructions

Please note that this test is to be used for patients on high-dose vitamin C (e.g., cancer therapy) in which results are expected to be very high relative to the reference interval.

Please note that this test is to be used for patients on high-dose vitamin C (eg, cancer therapy) in which results are expected to be very high relative to the reference interval.

Please note that this test is to be used for patients on high-dose vitamin C (e.g., cancer therapy) in which results are expected to be very high relative to the reference interval.


Expected Turnaround Time

3 - 5 days


Related Documents


Specimen Requirements


Specimen

Plasma, frozen and protected from light


Volume

1 mL


Minimum Volume

0.5 mL (Note: This volume does not allow for repeat testing.)


Container

Green-top (lithium heparin) tube; amber plastic transport tube with amber-top. (If amber tubes are unavailable, cover standard transport tube completely, top and bottom, with aluminum foil. Identify specimen with patient name directly on the container and on the outside of the aluminum foil. Secure with tape.) For amber plastic transport tube and amber-top, order Labcorp No. 23594.

Green-top (lithium heparin) tube; amber plastic transport tube with amber-top. (If amber tubes are unavailable, cover standard transport tube completely, top and bottom, with aluminum foil. Identify specimen with patient name directly on the container and on the outside of the aluminum foil. Secure with tape.) For amber plastic transport tube and amber-top, order LabCorp No. 23594.

Green-top (lithium heparin) tube; amber plastic transport tube with amber-top. (If amber tubes are unavailable, cover standard transport tube completely, top and bottom, with aluminum foil. Identify specimen with patient name directly on the container and on the outside of the aluminum foil. Secure with tape.) For amber plastic transport tube and amber-top, order Labcorp No. 23594.


Collection

Collect blood by venipuncture into a green-top containing lithium heparin and mix immediately by gentle inversion at least six times to ensure adequate mixing. Plasma must be separated from cells immediately after venipuncture and transferred to light-protected amber plastic tube. Separated plasma must be placed on dry ice for shipment within 4 hours of separation. To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested.


Storage Instructions

Freeze immediately and protect from light.


Stability Requirements

TemperaturePeriod
Room temperatureUnstable
RefrigeratedUnstable
Frozen14 days
Freeze/thaw cyclesStable x1

Causes for Rejection

Anticoagulants other than lithium heparin; specimen not protected from light


Test Details


Use

This test is used for the evaluation of vitamin C levels.

Evaluation of vitamin C levels

This test is used for the evaluation of vitamin C levels.


Limitations

This test was developed and its performance characteristics determined by Labcorp. It has not been cleared or approved by the Food and Drug Administration.

This test was developed and its performance characteristics determined by LabCorp. It has not been cleared or approved by the Food and Drug Administration.

This test was developed and its performance characteristics determined by Labcorp. It has not been cleared or approved by the Food and Drug Administration.


Methodology

Liquid chromatography-tandem mass spectrometry (LC/MS-MS)


Reference Interval

0.4–2.0 mg/dL

0.4–2.0 mg/dL


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