Analysis of the Monoclonal Antibody Adalimumab in Human Blood Collected via Volumetric Adsorptive Microsampling (VAMS) Technology and Utilizing LC-MS/MS Detection

July Land O' Lakes 2019 -- A study assessing the feasibility of performing quantitative analysis of adalimumab in human whole blood collected using Mitra� (Neoteryx) volumetric adsorptive microsampling (VAMS) devices was conducted. Adalimumab (Humira�) was chosen as a representative monoclonal antibody therapeutic to assess the practicality of protein analysis via LC-MS/MS analysis coupled with VAMS technology.