With a broad range of disseminated and subcutaneous tumor models characterized in NSG mice, and a scientific team that knows how to apply them, we can guide selection of the right tumor model for your CAR T cell or other ACT study.
| Leukemia [AML] | |
|---|---|
| Human | Mouse |
EOL-1 | C1498 |
| Leukemia [B-ALL] |
|---|
| Human |
| NALM6 NALM6-Luc-MCh-Puro Reh Reh (pMMP-Luc-Neo) RS4;11 |
| Lymphoma [B-Cell] | |
|---|---|
| Human | Mouse |
| DB DB/M2 | A20 A20-Luc2-Puro |
| Lymphoma [B-NHL] |
|---|
| Human |
| Farage GRANTA-519 |
| Lymphoma [Burkitt’s] |
|---|
| Human |
| B-JAB Daudi Daudi-Luc-mCh-Puro NAMALWA Raji Raji-Luc Ramos Ramos-Luc |
| Lymphoma [DLBCL] |
|---|
| Human |
| OCI-Ly1 LN OCI-Ly19-Luc-Neo OCI-Ly3-Luc-mCh-Puro OCI-Ly7-Luc-mCh-Puro (rescued) OCI-Ly7-Luc-Neo Pfeiffer SU-DHL-10 SU-DHL-10-LN-High SU-DHL-16 SU-DHL-4-Luc-mCh-Puro SU-DHL-8 TMD8 Toledo-Luc-Neo WSU-DLCL2 |
| Myeloma | |
|---|---|
| Human | Mouse |
| JJN-3-Luc MM.1S (pMMP-Luc-Neo) NCI-H929 NCI-H929-Luc-mCh-Puro OPM-2 RPMI 8226 U266B1 | 5TGM1-Luc J558 |
| Brain | |
|---|---|
| Human | Mouse |
| BT142 D54-Luc DBTRG (tumor) DBTRG-05MG Gli36-DsRed-R-Luc (rescued) LN-18 LN-229 LN-827(pMMP-LucNeo) M059K SF-295 SF-539 SF-767 SNB-19 U-87 MG U-87 MG-Luc U251 U251-Luc-mCh-Puro | GL261 GL261-Luc2 |
| Liver | |
|---|---|
| Human | Mouse |
| Hep 3B2.1-7 Hep G2 | BNL 1ME A.7R.1 BNL 1ME A.7R.1-Luc-mCh-Puro Hep55.1c Hepa 1-6 Hepa 1-6-Luc-mCh-Puro |
| Lung |
|---|
| Mouse |
| LL LL/2 LL/2-Luc-M38 |
| Lung [Adenosquamous] |
|---|
| Human |
| NCI-H596 |
| Lung [Anaplastic Carcinoma] |
|---|
| Human |
| Calu-6 |
| Lung [Bronchioalveolar] |
|---|
| Human |
| NCI-H322M |
| Lung [NSCLC] |
|---|
| Human |
| A549 A549-Luc-C8 Calu-1 Calu-3 HCC827 HCC827-Luc-mCh-Puro NCI-H125 NCI-H125-Luc NCI-H1299 NCI-H1650 NCI-H1703 NCI-H1703-Luc-mCh-Puro NCI-H1975 NCI-H1975-Luc NCI-H2110 NCI-H2122 NCI-H23 NCI-H292 NCI-H3122 NCI-H441 NCI-H460 NCI-H460-Luc2 NCI-H522 PC-9 |
| Lung [SCLC] |
|---|
| Human |
| DMS 114 NCI-H446 NCI-H69 NCI-H82 SHP-77 |
| Lung [Squamous] |
|---|
| Human |
| EBC-1 SK-MES-1 |
| Mammary/Breast | |
|---|---|
| Human | Mouse |
| BT-20 BT-474 HCC70 Hs 578Bst Hs 578T MCF 10A MCF-7 MCF7-Luc-mCh-Puro MDA-MB-231 MDA-MB-231-2LMP MDA-MB-231-Luc-D3H1 MDA-MB-231-Luc-D3H2 MDA-MB-231-Luc-D3H2LN MDA-MB-231-Luc-D3H3 MDA-MB-361 MDA-MB-453 MDA-MB-468 MX-1-Luc SK-BR-3 T47D UISO-BCA-1 ZR-75-1 | 4T1-luc2 E0771 EMT-6 MMTV-PyMT |
| Ovarian | |
|---|---|
| Human | Mouse |
| A2780 A2780-Luc IGROV1 IGROV1-Luc-Mch-Puro NIH:OVCAR-3 NIH:OVCAR-3-Luc-mCh-Puro OV-90 OVCAR-4 OVCAR-5 OVCAR-5-Luc-mCh-Puro OVCAR-8 OVCAR-8-Luc-mCh-Puro SK-OV-3 SKOV-3-luc-D3 | ID8 ID8-Luc-mCh-Puro |
| Prostate |
|---|
| Human |
| 22Rv1 CWR-22-R DU 145 DU 145-Luc LnCap clone FGC PC-3 PC-3-Luc PC-3M-Luc-C6 VCaP |
