Histotype
Mammary/Breast
| Parameter | Information |
|---|---|
| Strain | C57BL/6 |
| Implant Type | Cells |
| Implant Location | Mammary Fat Pad |
| Time to Staging | 20 days |
| Time to Evaluation Size (days) | 33.0 days |
| Td | 5.2 days |
The above parameters are from one study. For further information on this cell line and other parameters, including different strains, vendors, implant type and location and/or standards of care, please contact us.
Tumor Line
Mouse
Ref #
2896
Spotlight on E0771
Learn more about this cell line in our scientific spotlights:
Triple negative breast cancer (TNBC) is a complex and aggressive subtype of breast cancer lacking estrogen receptor, progesterone receptor, and HER2 amplifications; making it difficult to target therapeutically. Consequently, there’s a constant demand for better treatment options for TNBC. To help address the need for TNBC models, we highlighted the EMT6 model last month and herein we put forth the E0771 model, another TNBC syngeneic model for use in preclinical immuno-oncology. The E0771 cell line is a spontaneously developing medullary breast adenocarcinoma from C57BL/6 mice.[1] Parental E0771 is poorly metastatic when compared to 4T1[2] and has homozygous mutations in the Trp53 and KRAS genes.[3]