Biodistribution Assessment of Lipid Nanoparticle-Mediated mRNA Delivery Using In Vivo Imaging

Cayman Chemical’s LNP development services in partnership with Labcorp utilizes in vivo imaging technology to create a comprehensive LNP screening platform. With this approach, three LNP formulations were assessed in vitro and in vivo for potency of reporter gene expression and differential organ delivery. This comprehensive LNP formulation, characterization, and analysis service can be used to identify candidate LNP formulations with tissue-tropic distribution.