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MMP-9 (Matrix Metalloproteinase-9)

CPT 83520
Synonyms
  • Matrix Metalloproteinase-9

Test Details

Methodology

Enzyme-linked immunosorbent assay (ELISA)

Result Turnaround Time

3 - 7 days

Related Documents

For more information, please view the literature below.

Procedures for Hemostasis and Thrombosis: A Clinical Test Compendium

Specimen Requirements

Limitations

Results for this test are for research purposes only by the assay's manufacturer. The performance characteristics of this product have not been established. Results should not be used as a diagnostic procedure without confirmation of the diagnosis by another medically established diagnostic product or procedure.

References

Gress TM, Müller-Pillasch F, Lerch MM, Friess H, Büchler M, Adler G. Expression and in-situ localization of genes coding for extracellular matrix proteins and extracellular matrix degrading proteases in pancreatic cancer. Int J Cancer. 1995 Aug 9; 62(4):407-413.7635566
John A, Tuszynski G. The role of matrix metalloproteinases in tumor angiogenesis and tumor metastasis. Pathol Oncol Res. 2001; 7(1):14-23.11349215
Muroski MG, Roycik MD, Newcomer RG, et al. Matrix metalloproteinase-9/gelatinase B Is a putative therapeutic target of chronic obstructive pulmonary disease and multiple sclerosis. Curr Pharm Biotechnol. 2008 Feb; 9(1):34-46.18289055

Custom Additional Information

MMP-9 is a marker of inflammation, tissue remodeling, wound healing, and mobilization of tissue-bound growth factors and cytokines. Its expression correlates with abnormal collagen deposition accompanying pancreatic cancer, with lymph node metastasis in breast cancer and with regional vessel invasion by giant cell tumor or bone. MMP-9 contributes to the pathogenesis of numerous clinical disease states, including rheumatic arthritis, coronary artery disease, chronic obstructive pulmonary disease, multiple sclerosis, asthma, and cancer. Current research is exploring the role of this enzyme as a potential drug target.

Specimen

Serum, frozen

Volume

1 mL

Minimum Volume

0.5 mL

Container

Gel-barrier tube

Storage Instructions

Freeze. Stable at room temperature for 30 minutes.

Collection Instructions

Transfer serum to a plastic transport tube before freezing. To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested.

Reference Range

0−983 ng/mL

LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
500124 MMP-9 (Matrix metalloprot.-9) 500125 MMP9 ng/mL 60243-3
Order Code500124
Order Code NameMMP-9 (Matrix metalloprot.-9)
Order Loinc
Result Code500125
Result Code NameMMP9
UofMng/mL
Result LOINC60243-3