Paliperidone (as 9-Hydroxyrisperidone), Serum or Plasma

CPT: 80342
Updated on 5/12/2019
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Test Details


  • 9-Hydroxyrisperidone
  • Invega®


Therapeutic drug management


Liquid chromatography/tandem mass spectrometry (LC/MS-MS)

Reference Interval

20−60 ng/mL

Specimen Requirements


Serum or plasma


3 mL

Minimum Volume

0.6 mL


Red-top tube or green-top (heparin) tube. Gel-barrier tubes are not recommended.

Patient Preparation

Trough levels are most reproducible.


Transfer separated serum or plasma in a plastic transport tube.

Serum or plasma must be separated from cells within 45 minutes of venipuncture. Submit serum or plasma in a plastic transport tube.

Transfer separated serum or plasma in a plastic transport tube.

Storage Instructions

Submission/transport (<3 days): Room temperature. For storage beyond three days, specimen should be refrigerated or frozen.

Causes for Rejection

Gel-barrier tubes


Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
790856 Paliperidone, Serum 790857 9-Hydroxyrisperidone ng/mL 9383-1

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